High purity Vitamin E succinate with good quality

Product Name:

Vitamin E succinate

Synonyms:

(+)-nyl)este;(2r-(2r*(4r*,8r*)))-cyl)-2h-1-benzopyran-6-yl)este;[2theta-[2theta(4theta,8theta)]]-cyl)-2h-1-benzopyran-6-yl]este;alpha-tocopherol,succinate;alpha-tocopherolhemisuccinate;butanedioicacid,mono(3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride;butanedioicacid,mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltride;mono[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]ester,[2R-Butanedioicacid

CAS:

4345-03-3

MF:

C33H54O5

MW:

530.78

Product Categories:

Vitamins and derivatives;Vitamin Ingredients;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;1185IU/1210IU

Mol File:

4345-03-3.mol

Chemical Properties

melting point 

~76 °C(lit.)

boiling point 

625.8 °C at 760 mmHg

density 

1.002 g/cm3

flashing point 

187 °C

vapor pessure 

1.58E-16 mmHg at 25°C

solubility 

Insoluble in water

storage temp. 

2-8°C

Item

standard

Acidity

18.0-19.3ml

Potency, IU/g

1185IU

1210IU

d-α tocopheryl acid succinate, MIN

96%-102%

96%-102%

Heavy metals (as Pb)

10ppm (MAX)

Specific rotation, [a]d25, degrees

+24 (MIN)

Usage And Synthesis

Chemical Properties

White to Off-white Crystalline Powder

Usage

A potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand). It inhibits proliferation of mesothelioma cells by selective down-regulation of fibroblast growth factor receptors. Furthermore, it has been shown to enhance the anti-tumor effect of dendritic cell vaccines.

Reactivity Profile

Vitamin E succinate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Flash point data for Vitamin E succinate are not available; however, Vitamin E succinate is probably combustible.