Ezetimide，SCH-58235

Min.Order / FOB Price:Get Latest Price

100 Gram	FOB Price: USD 1.0000

100 Gram

FOB Price: USD 1.0000

Min.Order :100 Gram
Purity: ≥98.0%
Payment Terms : L/C

Keywords

163222-33-1 Ezetimide，SCH-58235 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one EZETIMIBE ZETIA Ezitimibe&Int EzetimibeC24H21F2N03 (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3

Quick Details

Appearance:White crystal
Application:Pharmaceutical intermediates
PackAge:100g,500g,1kg,25kg/drum
ProductionCapacity:1000|Gram|Month
Storage:Dry seal
Transportation:shipping

Superiority:

98%

Details:

Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density lipoprotein (LDL) cholesterol when added to statin treatment.
IC50 value:
Target: cholesterol-absorption
Ezetimibe is a lipid-lowering drug that inhibits the intestinal absorption of dietary and biliary cholesterol by blocking passage across the intestinal wall. In patients with familial hypercholesterolemia, combined therapy with ezetimibe and simvastatin did not result in a significant difference in changes in intima-media thickness, as compared with simvastatin alone, despite decreases in levels of LDL cholesterol and C-reactive protein. (ClinicalTrials.gov number, NCT00552097.) Ezetimibe offers a new therapeutic option for patients receiving statins who require further reduction in LDL cholesterol.

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