302962-49-8 Dasatinib

Details:

Dasatinib Basic information
Product Name: Dasatinib
Synonyms: Dasatinib(BMS-354825);BMS-354825;N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-;Dasatinib;N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide;N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide;2-{6-[4-(2-HYDROXY-ETHYL)-PIPERAZIN-1-YL]-2-METHYL-PYRIMIDIN-4-YLAMINO}-THIAZOLE-5-CARBOXYLIC ACID (2-CHLORO-6-METHYL-PHENYL)-AMIDE
CAS: 302962-49-8
MF: C22H28ClN7O3S
MW: 488.01
EINECS:
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Pharmaceutical intermediate;Inhibitor;Sprycel;Anti-cancer&immunity;Inhibitors
Mol File: 302962-49-8.mol
Dasatinib Structure
Dasatinib Chemical Properties
mp  275-286°C
storage temp.  -20°C Freezer
CAS DataBase Reference 302962-49-8(CAS DataBase Reference)
Safety Information
MSDS Information
Dasatinib Usage And Synthesis
Chemical Properties Pale-Yellow Solid
Usage A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic
Usage Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of ＜1 nM, 0.8 nM and 79 nM, respectively.
Dasatinib Preparation Products And Raw materials

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