Buy High quality Ab...

Buy High quality Abiraterone producer

Buy High quality Abiraterone producer

Min.Order / FOB Price:Get Latest Price

1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: 99
  • Payment Terms : L/C,D/A,D/P,T/T

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Buy Abiraterone High quality Abiraterone Abiraterone producer

Quick Details

  • Appearance:White Solid
  • Application:Abiraterone, a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currentl
  • PackAge:According to your demand
  • ProductionCapacity:1|Metric Ton|Month
  • Storage:Refrigerator
  • Transportation:as requested

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Buy High quality Abiraterone producer

Abiraterone is a new type of hormone therapy. It is also called abiraterone acetate, CB7630 or Zytiga. It is used to treat prostate cancer that has spread to other parts of the body. It may help some men to live longer. It can also help control symptoms. Clinical trials are also using abiraterone for earlier stages of prostate cancer and advanced breast cancer. Abiraterone is associated with a not uncommon rate of serum enzyme elevation during therapy, but has not been clearly linked to cases of clinically apparent liver injury with jaundice.

On April 28, 2011, the U.S. Food and Drug Administration approved abiraterone acetate (Zytiga Tablets, Centocor Ortho Biotech, Inc.) for use in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) who have received prior chemotherapy containing docetaxel.

Abiraterone is a steroidal compound with antiandrogen activity. it is a Cytochrome P450 17A1 Inhibitor. The mechanism of action of abiraterone is as a Cytochrome P450 17A1 Inhibitor, and Cytochrome P450 2D6 Inhibitor, and Cytochrome P450 2C8 Inhibitor that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.

Chemvon Biotechnology is one of the leading high-technology manufacturer in the field of pharmaceutical and fine chemical industry.

From origins as a research group in technology service, chemvon has progressed into an integrated company with a kilo lab and a pilot plant offering a range of APIs, NCEs and some organic intermediates.

Abiraterone is our regular products. 

 

Details:

Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC50s of 2.5 nM and 15 nM, respectively.

Product Number A2868
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C24H31NO = 349.52  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 154229-19-3
Reaxys Registry Number 7309269
PubChem Substance ID 253661112
MDL Number

MFCD00924100

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