CasNo.120373-24-2,Unoprostone best price / fast delivery /on hot selling,Isopropyl unoprostone(120373-24-2) Suppliers

1 Gram	Negotiable

Min.Order :1 Gram
Purity: 99
Payment Terms : L/C,T/T

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Application:Isopropyl unoprostone (120373-24-2) is an antiglaucoma and mainly used in treatment of ocular hypert
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Unoprostone best price / fast delivery /on hot selling

Unoprostone isopropyl ester (Rescula) is the clinically approved, prodrug form of unoprostone, which is a free acid analog of prostaglandin F_2α (PGF_2α). Both latanoprost and Rescula have been approved for the treatment of ocular hypertension. Both analogs of PGF_2α are believed to act by increasing the rate of aqueous humor outflow through the uveoscleral pathway. Both drugs are believed to act as prodrugs, with endogenous esterases within the eye releasing the free acid active form of the drug. The typical does of Rescula (one drop of 0.12% solution) is nearly 100 times that of latanoprost.Rescula has very little activity on isolated DP or TP receptors, less than 0.0005% the activity of PGE₂ on EP₃ receptors, and about 3% of the activity of PGF_2α on FP receptors.

Unoprostone isopropyl ester is a free acid analog of prostoglandin F_2α (sc-203219), the prodrug form of unoprostone (sc-205536). Both analogs are believed to act by increasing the rate of aqueous humor outflow through

Details:

Catalogue Number	U800050
Chemical Name	Unoprostone Isopropyl Ester
Synonyms	(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopenthyl]-5-heptenoic Acid Isopropyl Ester; UF-021; Rescula;
CAS Number	120373-24-2
Molecular Formula	C??H??O?
Appearance	Clear Colourless Oil
Melting Point	N/A
Molecular Weight	424.61
Storage	-20°C Freezer
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Category	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	Antiglaucoma; used in treatment of ocular hypertension.