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Nomegestrol acetate, 17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate,is being investigated as the progestin component of anew oral contraceptive, in combination with the estrogenestradiol. This new combination, NOMAC/E2, is in phaseIII trials and would be the first oral contraceptive to utilizeestradiol itself as the estrogenic component. Structurally,NOMAC is considered a nor-progesterone derivative thatlacks the C19 methyl group in megestrol acetate.
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Catalogue Number | N635850 |
Chemical Name | Nomegestrol |
Synonyms | 17-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione; Monaco; Thermex; |
CAS Number | 58691-88-6 |
Molecular Formula | C??H??O? |
Appearance | White to Off-White Solid |
Melting Point | 199 - 203°C |
Molecular Weight | 328.45 |
Storage | -20°C Freezer |
Solubility | Chloroform, DMSO (Slightly), Methanol (Slightly) |
Category | Standards; Steroids; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | A progestogen, derivatives of which are used in contraceptives and hormone therapies. |
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