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dutasteride dutasteride powder Lower price Dutasteride
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Dutasteride powder
1.Product profile:
Name:Dutasteride
Synonyms : (5alpha,17beta)-N-{2,5-Bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-l-ene-17-carboxamide
Molecular Formula : C27H30F6N2O2
Molecular Weight : 528.53
CAS:164656-23-9
2.Introduction
Dutasteride is a dual 5-α reductase inhibitor that inhibits conversion oftestosterone to dihydrotestosterone (DHT). Used for benign prostatic hyperplasia; however, it increases the risk of erectile dysfunction[1] and decreased sexual desire.[2]
3.Medical uses
Dutasteride useful for the symptoms of benign prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate".
In those who are being regularly screened 5-alpha-reductase inhibitor(finasteride and dutasteride) reduce the overall risk of being diagnosed with prostate cancer however there is insufficient data to determine if they have an effect on the risk of death and may increase the chance of more serious cases.
4. Specification
Contents of testing |
Specifications |
Results |
Appearance |
White or off-white crystalline powder |
Complies |
Solubility |
Soluble in dichloromethane, slightly soluble in ethyl acetate, methanol, acetronile, insoluble in water |
Complies |
Identification (IR) |
Should match with working standard |
Complies
|
Melting point |
246.0°C~252.0°C |
248.0°C~249.5°C |
Water by KF |
Not more than 0.5% |
0.05% |
Loss on drying |
Not more than 0.5% |
0.03% |
Residue on ignition % |
Not more than 0.2% |
0.05% |
Heavy metal |
Not more than 20 ppm |
Complies |
Related Substances(HPLC) |
||
Single maximum impurity |
Not more than 0.5% |
0.31% |
Total impurities |
Not more than 1.0% |
0.64% |
Assay(HPLC,Base on drying) % |
98.0%-102.0% |
99.24% |
Conclusion: |
Conform with our Enterprise Standard |
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