Prednisone Acetate 125-10-0 11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3;4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate;delcortin;delta’-dehydrocortisoneacetate;delta-corlin;deltalone;nisone;ACETIC ACID 2-(
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Prednisone Acetate ,125-10-0
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4. Prednisone Acetate (CP)Specification
TESTS |
SPECIFICATIONS |
RESULTS |
Description |
A white or almost white crystalline powder |
A white crystalline powder |
Specific rotation |
Between +183°~+190° |
+187.19° |
Absorptivity |
373~397 |
382.46 |
Identification |
Reaction is red |
Reaction is red |
Become a turquoise |
Become a turquoise |
|
Retention time is consistent with the retention time of the reference solution |
Conforms |
|
IR absorption meets specification(Spectrum set 549 figure) |
Conforms |
|
Related substances |
Prednisone≤0.5% |
0.06% |
Cortisone acetate≤1.5% |
0.56% |
|
Total impurities≤2.0% |
0.76% |
|
Loss on drying |
≤0.5% |
0.12% |
Assay |
97.0~102.0% |
98.45% |
Residual solvents |
Ethanol≤5000ppm |
1056ppm |
Ethyl acetate≤5000ppm |
ND |
|
Packaging and storage |
Store protected from light. |
|
CONCLUSION |
Conform to CP2010 monograph |
Biochemical studies, adrenal cortical hormone drugs, anti-inflammatory, anti-allergic, and so on.
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