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Betamethasone Dipropionate 5593-20-4 BETAMETHASONE DIPROPIONATE;BETAMETHASONE 17,21-DI-PROPIONATE;BETAMETHASONE 17-ALPHA,21-DIPROPIONATE;1,4-PREGNADIEN-9-ALPHA-FLUORO-16-BETA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 17,21-DIPROPIONATE;9ALP
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Betamethasone Dipropionate
1. CAS No.: 5593-20-4
2. Quality: USP35
3. Specification of Betamethasone Dipropionate
Items | Specifications | Results |
Character | White to almost white crystalline powder | Almost white crystalline powder |
Identification | 1) Complies by IR | Conforms |
2) Complies by TLC | Conforms | |
Specific rotation | +63°to +70° | +67.7° |
Related substances | Individual impurity not more than 1.0% | 0.04% |
Total impurity not more than 2.0% | 0.12% | |
Loss on drying | Not more than 1.0% | 0.10% |
Residue on drying | Not more than 0.2% | 0.08% |
Residue solvents | Acetone: not more than 5000ppm | 656ppm |
Methanol; not more than 3000ppm | 104ppm | |
Chloroform: not more than 60ppm | Undetected | |
Assay | It should contain 97.0% to 103.0% of C28H37FO7 calculated on dried basis | 100.30% |
Conclusion | The results can conform with USP35 |
5. Usage of Betamethasone Dipropionate
Betamethasone Dipropionate is a "super high potency" corticosteroid used to treat inflamatory skin conditions
such as dermatitis, eczema and psoriasis.
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