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1 Kilogram |
FOB Price: USD 1.0000 |
Clobetasol propionate 25122-46-7 17-propionate;cgp9555;clobesol;pregna-1,4-diene-3,20-dione,21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-me;CLOBESTASOL PROPIONATE;CLOBETASOL-17-PROPIONATE;CLOBETASOLE PROPIONATE;CLOBETASOL PROPIONA
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Specification of Clobetasol Propionate:
Items | Specifications | Results |
Appearance | White to cream, crystalline powder | Whitecrystalline Powder |
Identification (By IR) | Conforms to CRS spectrum | Conforms |
Melting point | Approximately 196℃ | 197℃ |
Specific rotation | +98°~+104°(dried substance) | +101.1° |
Loss on drying | ≤2.0% | 0.20% |
Residue on ignition | ≤0.1% | 0.08% |
Heavy metals | ≤20ppm | Conform |
Related substances | ||
Any impurity | ≤1.0% | 0.21% |
Total impurities | ≤2.5% | 0.63% |
Assay (by HPLC) | Contains 97.0% to 102.0% of C25H32ClFO5, calculated on dried basis | 99.50% |
Conclusion | It conforms to USP37 |
Usage of Clobetasol propionate
Clobetasol propionate is used for the treatment of various skin disorders including ezema, herpeslbialis, psoriasis,
and lichen sclerosus, it is also used to treat severalauto-immune diseases including alopecia areata, vitiligo,
lichen planus (auto immune skin nodules), and mycosis fungoides (T-cell skin lymphoma). It is used as first-line
treatment for both acute and chronic GVHD of the skin
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