Abacavir Sulfate 188062-50-2 ZIAGEN;ABACAVIR SULPHATE;ABACAVIR SULFATE;(1S,4R)-4-[2-AMINO-6-(CYCLOPROPYLAMINO)-9H-PURIN-9-YL]-2-CYCLOPENTENE-1-METHANOL, SULFATE;Ziagen, (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyc
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Product Name:Abacavir Sulfate
Cas No.: 188062-50-2
Molecular Formula: C28H38N12O6S
Molecular Weight: 670.74
Tests and Methods |
Specifications |
Appearance |
White to off white Crystalline powder |
Identification |
IR Identical |
HPLC Identical |
|
Sulfate Identical |
|
Water |
N.M.T. 1.0% |
Residue on Ignition |
N.M.T. 0.2% |
Heavy Metals |
N.M.T. 0.002% |
Limit of the abacavir enantiomer |
N.M.T. 0.2% |
Purity 1)Related Substances |
Descyclopropyl abacavir: N.M.T. 0.1% |
Dihydro abacavir: N.M.T. 0.1% |
|
Abacavir penultimate:N.M.T. 0.1% |
|
O-Pyrimidinyl abacavir:N.M.T. 0.15% |
|
Unknown impurities: 0.1% |
|
Total impurities:0.5% |
|
2) Residual solvents |
Methanol: N.M.T. 0.5% |
Acetone: N.M.T. 0.5% |
|
Ethanol: N.M.T. 0.5% |
|
Content of sulfate |
13.6~15.0% |
Assay |
98.0~102.0% (calculated on anhydrous and solvent free basis) |
Conclusion |
The product confirm the enterprise standard |
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