PF04418948 PF-04418948 PF 04418948
PF-04418948 is a potent and selective prostaglandin EP? receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. www.bocsci.com/pf-04418948-cas-1078166-57-0-item-470809.html
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