JNJ31020028 JNJ 31020028 JNJ-31020028
JNJ-31020028 is a selective brain penetrant small molecule antagonist of the neuropeptide Y Y(2) receptor. JNJ-31020028 bound with high affinity (IC50 = 8.07, human) and was 100-fold selective versus human Y(1), Y(4), and Y(5) receptors. JNJ-31020028 was demonstrated to be an antagonist (pK(B) = 8.04) in functional assays. www.bocsci.com/jnj-31020028-cas-1094873-14-9-item-456933.html
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