- Min.Order :1 Gram
- Purity: 98%
- Payment Terms : L/C
Keywords
LOXO 101 LOXO101 ARRY-470
Quick Details
- Appearance:Solid powder
- Application:Inhibitor
- PackAge:
- ProductionCapacity:10|Kilogram|Month
- Storage:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
- Transportation:
Superiority:
LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. www.bocsci.com/loxo-101-arry-470-cas-1223403-58-4-item-470826.html
Details:
LOXO-101, also known as ARRY-470, is an orally bioavailable, potent, ATP-competitive inhibitor of TRKA, TRKB, and TRKC. LOXO-101 has IC50 values in the low nanomolar range for inhibition of all three TRK family members in binding and cellular assays, with 100x selectivity over other kinases, and has shown acceptable pharmaceutical properties and safety in nonclinical models. www.bocsci.com/loxo-101-arry-470-cas-1223403-58-4-item-470826.html
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