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2-Fluoro Adenosine 146-80-5 XANTHOSINE
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Uses | The deamination product of Guanosine. Potential biomarker for detecting radiation exposure. XANTHOSINE is used in the amplification of DNA isothermal strand displacement. |
Uses | Xanthosine-13C5, is the labeled analogue of Xanthosine (X742100), the deamination product of Guanosine. It is also a potential biomarker for detecting radiation exposure. |
Definition | ChEBI: A purine nucleoside in which xanthine is attached to ribofuranose via a beta-N9-glycosidic bond. |
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The first nucleotide product in purine nucleotide biosynthesis, the 6-hydroxypurine nucleotide. Under the catalysis of adenylate succinate synthetase, adenylate succinate is generated and then cleaved into adenine nucleotide (AMP), or oxidized to generate xanthine nucleotide (XMP) and then accept amino to synthesize guanine Nucleotides (GMP). IMPs are mainly found in transfer ribonucleic acid (tRNA). AMP is decomposed under the action of deaminase to generate IMP, and GMP is decomposed under the action of guanine nucleotide reductase to also generate IMP, that is, AMP and GMP can be converted to each other through IMP to maintain the balance of AMP and GMP content.
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