Eplerenone 107724-...

Eplerenone  107724-20-9

Eplerenone 107724-20-9

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1 Kilogram

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Keywords

107724-20-9 Eplerenone C24H30O6

Quick Details

  • Appearance:conform
  • Application:107724-20-9
  • PackAge:according to the demand of cusotmer
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:conform
  • Transportation:by air

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Details:

Eplerenone Basic information
Product Name: Eplerenone
Synonyms: (7A,11A,17A)-9,11-EPOXY-17-HYDROXY-3-OXO-PREGN-4-ENE-7,21-DICARBOXYLIC ACID G-LACTONE METHYL ESTER;EPLERENONE;EPLERINONE;pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-lactone methyl ester;EPLERENONE 98%;EPLERENONE USP STANDARD;Elperenone;EplerenoneC24H3006
CAS: 107724-20-9
MF: C24H30O6
MW: 414.49
EINECS:  
Product Categories: Antihypertensive;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Steroid and Hormone;Inspra;Cardiovascular APIs
Mol File: 107724-20-9.mol
Eplerenone Structure
 
Eplerenone Chemical Properties
mp  241-243°C
storage temp.  Store at RT
 
Safety Information
Hazardous Substances Data 107724-20-9(Hazardous Substances Data)
MSDS Information
 
 
Eplerenone Usage And Synthesis
Chemical Properties White Solid
Usage Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
Usage Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM. It is used as an adjunct in the management of chronic heart failure. It is similar to the diuretic spironolactone, though it may be more specific for the mineralocorticoid receptor and is sp
Usage anticancer agent
Biological Activity Selective mineralocorticoid (aldosterone) receptor antagonist (IC 50 = 360 nM). Displays > 27-fold selectivity over androgen, progesterone and estrogen receptors (IC 50 > 10 μ M). Orally active antihypertensive in vivo .

 

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