CAS:169590-42-5 C17H14F3N3O2S Celecoxib CAS:169590-42-5 C17H14F3N3O2S factory price high purity 99% CAS:169590-42-5 C17H14F3N3O2S technical grade or OLED grade
Celecoxib Basic information |
Product Name: | Celecoxib |
Synonyms: | CELEBREX;CELECOXIB;4-[[5-(4-METHYLPHENYL)-3-TRIFLUOROMETHYL]-1H-PYRAZOL-YL]BENZENESULFONAMIDE;4-[5-((4-METHYLPHENYL)-3-TRIFLUORPMETHYL)-1H-PYRAZOL-YL]BENENESULFONAMIDE;Celecoxib, 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide;Benzenesulfonamide, 4-5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl-;4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide;Celebra |
CAS: | 169590-42-5 |
MF: | C17H14F3N3O2S |
MW: | 381.37 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;All Inhibitors;Osteoarthritis and Rheumatoid Arthritis;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pfizer compounds;Sulfur & Selenium Compounds;Celecoxib;MONASIRUP |
Mol File: | 169590-42-5.mol |
Celecoxib Chemical Properties |
mp | 157-159°C |
storage temp. | Store at RT |
CAS DataBase Reference | 169590-42-5(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22-52-61-60 |
Safety Statements | 22-24/25-28-37/39 |
HazardClass | IRRITANT |
Hazardous Substances Data | 169590-42-5(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide | English |
Celecoxib Usage And Synthesis |
Chemical Properties | White to Pale Yellow Solid |
Usage | expectorant, gastric stimulant, insecticide |
Usage | For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis |
Usage | A selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis |
Biological Activity | Selective cyclooxygenase-2 (COX-2) inhibitor (IC 50 values are 15 and 0.04 μ M for COX-1 and COX-2 respectively). Anti-inflammatory with shorter plasma half-life in vivo than SC 58121 (5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole ). Displays chemopreventive activity in in vivo tumor models. |
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