- Min.Order :1 Kilogram
- Purity: 98%
- Payment Terms : L/C,D/P,T/T,
Keywords
2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol VORICONAZOLE (2R,3S/2S,3R)-3-(5-FLUORO-4-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIA
Quick Details
- Appearance:Cyrstalline Solid
- Application:Pharmaceuticals； APIs & Intermediate
- PackAge:as required
- ProductionCapacity:100|Kilogram|Month
- Storage:Store at +4°C
- Transportation: by sea/ by express
Superiority:
Henan Sunlake Enterprise Corporation
Our Advantages
1, Any inquiry about chemicals will be welome and replied within 24 hours;
2, Competitive price;
3, Good quality is guaranteed;
4, Fast and safe delivery;
5, Full experience in manufacture and international trade;
6, Perfect and professional service.
Details:
Product information
| Voriconazole Basic information |
| Product description Pharmacological interactions Application |
| Product Name: | Voriconazole |
| Synonyms: | 2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol;VORICONAZOLE;(2R,3S/2S,3R)-3-(5-FLUORO-4-PYRIMIDINYL)-2-(2,4-DIFLUOROPHENYL)-1-(1H-1,2,4-TRIA;(aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol;UK-10949;Vorionazole;(2R,3S)-2-(2,4-DIFLUOROPHENYL)-3-(5-FLUOROPYRIMIDIN-4-YL)-1-(1H-1,2,4-TRIAZOL-1-YL)BUTAN-2-OL;(aR,S)-a-(2,4-Difluorophenyl)-5-fluoro--methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol |
| CAS: | 137234-62-9 |
| MF: | C16H14F3N5O |
| MW: | 349.31 |
| EINECS: | 200-261-5 |
| Product Categories: | API;Antifungal (Systemic);Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Heterocycles;Pfizer compounds;Inhibitor;ZINACEF |
| Mol File: | 137234-62-9.mol |
|
|
|
| Voriconazole Chemical Properties |
| mp | 127-130°C |
| storage temp. | Store at +4°C |
| CAS DataBase Reference | 137234-62-9(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-36/38-52/53-48/22-40-25-61-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-36-45-36/37-22-53-16 |
| Voriconazole Usage And Synthesis |
| Product description | Voriconazole is a broad-spectrum triazole antifungal ,it is primarily used for the treatment of progressive, possibly life-threatening infections in immune deficiency patients. Indications include: immunosuppressed patients with severe fungal infections, acute invasive aspergillosis (the most common pathogen is Aspergillus fumigatus, followed by A. flavus, Aspergillus niger and Aspergillus soil), severe invasive infections caused by fluconazole-resistant Candida (including C. krusei) severe infection caused by Foot actinomycetes bacteria genus and Fusarium bacteria genus . Moderate to severe renal insufficiency is administered intravenously paying caution. |
| Pharmacological interactions |
Combination With the CYP3A4 substrates, terfenadine, sirolimus, astemizole, cisapride, pimozide or quinidine , can increase blood concentrations of this drug, leading to QT prolongation, and occasionally torsades de pointes ventricular tachycardia. Combination With Rifampicin, rifabutin, efavirenz, ritonavir (each 400mg, once every 12 hours), carbamazepine and phenobarbital, can significantly lower blood concentrations of voriconazole. Combination with ergot alkaloids (ergotamine, dihydroergotamine) plasma concentrations of ergot drugs can cause increased ergot poisoning. The above information is edited by the chemicalbook of Tian Ye. |
| Application | broad-spectrum antifungal |
| Chemical Properties | Cyrstalline Solid |
| Usage | An antifungal (systemic). An ergosterol biosynthesis inhibitor. |
| Usage | antibacterial |
| Usage | An antifungal. An Ergosterol Biosynthesis inhibitor |
| Biological Activity | Triazole antifungal agent. Displays potent activity against Candida , Cryptococcus and Aspergillus species. |
Henan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.
We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate.
You Might Also Like
Related Searches
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View