477-30-5 N-DEACETYL-N-METHYLCOLCHICINE 477-30-5 COLCEMID C21H25NO5 COLCHAMINE
Product Name: | DEMECOLCINE |
Synonyms: | N-DEACETYL-N-METHYLCOLCHICINE;N-DESACETYL-N-METHYLCOLCHICINE;N-METHYL-N-DEACETYL-COLCHICINE;COLCEMID;COLCEMIDE(R);COLCEMID(R);COLCHAMINE;DEMECOLCIN |
CAS: | 477-30-5 |
MF: | C21H25NO5 |
MW: | 371.43 |
EINECS: | 207-514-6 |
Product Categories: | All Inhibitors;Inhibitors |
Mol File: | 477-30-5.mol |
DEMECOLCINE Chemical Properties |
mp | 73-75°C |
storage temp. | 2-8°C |
solubility | DMSO: 10 mg/mL |
form | powder |
Safety Information |
Hazard Codes | T,T+ |
Risk Statements | 25-26/27/28 |
Safety Statements | 22-24/25-45-36/37/39 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | GH0800000 |
F | 8-10-23 |
HazardClass | 6.1(a) |
PackingGroup | II |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
DEMECOLCINE Usage And Synthesis |
Chemical Properties | Faintly Yellow Crystalline Powder |
Usage | An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. |
Usage | Inhibitor of spindle fiber formation |
DEMECOLCINE Preparation Products And Raw materials |
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Product Name: | DEMECOLCINE |
Synonyms: | N-DEACETYL-N-METHYLCOLCHICINE;N-DESACETYL-N-METHYLCOLCHICINE;N-METHYL-N-DEACETYL-COLCHICINE;COLCEMID;COLCEMIDE(R);COLCEMID(R);COLCHAMINE;DEMECOLCIN |
CAS: | 477-30-5 |
MF: | C21H25NO5 |
MW: | 371.43 |
EINECS: | 207-514-6 |
Product Categories: | All Inhibitors;Inhibitors |
Mol File: | 477-30-5.mol |
DEMECOLCINE Chemical Properties |
mp | 73-75°C |
storage temp. | 2-8°C |
solubility | DMSO: 10 mg/mL |
form | powder |
Safety Information |
Hazard Codes | T,T+ |
Risk Statements | 25-26/27/28 |
Safety Statements | 22-24/25-45-36/37/39 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | GH0800000 |
F | 8-10-23 |
HazardClass | 6.1(a) |
PackingGroup | II |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
DEMECOLCINE Usage And Synthesis |
Chemical Properties | Faintly Yellow Crystalline Powder |
Usage | An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. |
Usage | Inhibitor of spindle fiber formation |
DEMECOLCINE Preparation Products And Raw materials |
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