50847-11-5 C14H18N2O Ibudilast

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

50847-11-5 IBUDILAST-D7 50847-11-5 KC-404 C14H18N2O propanon

Quick Details

Appearance:White Solid
Application:50847-11-5
PackAge:As customer's requirment
ProductionCapacity:100-200|Kilogram|Month
Storage:2-8°C
Transportation:By air or sea or express

Superiority:

Product Name:	Ibudilast
Synonyms:	IBUDILAST;IBUDILAST-D7;KC-404;1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL];2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine;2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL]-1-PROPANONE;3-ISOBUTYRYL-2-ISOPROPYLPYRAZOLO(1,5-A)PYRIDINE;2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-1-propanon
CAS:	50847-11-5
MF:	C14H18N2O
MW:	230.31
EINECS:
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Cyclic Nucleotide related;Amines;Heterocycles;Inhibitors
Mol File:	50847-11-5.mol

Ibudilast Chemical Properties

mp	53-54°C
density	1.09
storage temp.	2-8°C
solubility	DMSO: 28 mg/mL, soluble
form	solid
color	white
CAS DataBase Reference	50847-11-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	UR0711200

MSDS Information

Provider	Language
2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone	English
SigmaAldrich	English

Ibudilast Usage And Synthesis

Chemical Properties	White Solid
Usage	a phosphodiesterase inhibitor with anti-inflammatory activity
Usage	A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral)
Biological Activity	Phosphodiesterase inhibitor (IC 50 values are 53, 35, 48, 12 and 10 mM for PDE Ia, II, III, IV and V respectively). Inhibits platelet aggregation and is an orally-active cerebral vasodilator, bronchodilator and antiallergic agent.

Ibudilast Preparation Products And Raw materials

Raw materials

Sodium acetate-->2-Picoline-->Isobutyric anhydride

Our Services

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
6.Packing pictures and loading video before loading
7.Free Sample
9.Factory audit
10.Strong after-sale service

Our Services

1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. We can provide mixed containers with different mixed items in one container

Details:

Product Name:	Ibudilast
Synonyms:	IBUDILAST;IBUDILAST-D7;KC-404;1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL];2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine;2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL]-1-PROPANONE;3-ISOBUTYRYL-2-ISOPROPYLPYRAZOLO(1,5-A)PYRIDINE;2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-1-propanon
CAS:	50847-11-5
MF:	C14H18N2O
MW:	230.31
EINECS:
Product Categories:	Intermediates & Fine Chemicals;Pharmaceuticals;Cyclic Nucleotide related;Amines;Heterocycles;Inhibitors
Mol File:	50847-11-5.mol

Ibudilast Chemical Properties

mp	53-54°C
density	1.09
storage temp.	2-8°C
solubility	DMSO: 28 mg/mL, soluble
form	solid
color	white
CAS DataBase Reference	50847-11-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	UR0711200

MSDS Information

Provider	Language
2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone	English
SigmaAldrich	English

Ibudilast Usage And Synthesis

Chemical Properties	White Solid
Usage	a phosphodiesterase inhibitor with anti-inflammatory activity
Usage	A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral)
Biological Activity	Phosphodiesterase inhibitor (IC 50 values are 53, 35, 48, 12 and 10 mM for PDE Ia, II, III, IV and V respectively). Inhibits platelet aggregation and is an orally-active cerebral vasodilator, bronchodilator and antiallergic agent.