CasNo.60-56-0,CAS:60-56-0 C4H6N2S Methimazole,(60-56-0) Suppliers

500 Gram	Negotiable

Min.Order :500 Gram
Purity: 99%
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CAS:60-56-0 C4H6N2S Methimazole CAS:60-56-0 C4H6N2S factory price high purity 99% CAS:60-56-0 C4H6N2S technical grade or OLED grade

Quick Details

Appearance:white poweder
Application:CAS:60-56-0 C4H6N2S technical grade or OLED grade
PackAge:Plastic vacuum packaging bag or bucket
ProductionCapacity:1|Metric Ton|Day
Storage:under the cool and dry area
Transportation:by express or by sea

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Methimazole Basic information

Imidazole anti-thyroid drugs Chemical properties Application Production methods

Product Name:	Methimazole
Synonyms:	TAPAZOLE;THIAMAZOLE;1,3-dihydro-1-methyl-2h-imidazole-2-thion;1,3-dihydro-1-methyl-2H-Imidazole-2-thione;1-methyl-2-mercapto-imidazol;1-methyl-imidazole-2-thio;1-Metylo 2 merkaptoimidazolem;1-metylo2merkaptoimidazolem
CAS:	60-56-0
MF:	C4H6N2S
MW:	114.17
EINECS:	200-482-4
Product Categories:	Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Bioactive Small Molecules;Building Blocks;Cell Biology;Chemical Synthesis;Heterocyclic Building Blocks;Imidazoles;M;API;TAPAZOLE;Other APIs;Medicine Intermediates
Mol File:	60-56-0.mol

Methimazole Chemical Properties

mp	144-147 °C(lit.)
bp	280 °C
Fp	280°C
storage temp.	Refrigerator
Water Solubility	soluble
Merck	14,5971
BRN	108646
CAS DataBase Reference	60-56-0(CAS DataBase Reference)
NIST Chemistry Reference	Methimazole(60-56-0)
EPA Substance Registry System	2H-Imidazole-2-thione, 1,3-dihydro-1-methyl-(60-56-0)

Safety Information

Hazard Codes	Xn
Risk Statements	43-62-63-22
Safety Statements	26-27-36-45-36/37
WGK Germany	3
RTECS	NI8615000
HS Code	29332990
Hazardous Substances Data	60-56-0(Hazardous Substances Data)

MSDS Information

Provider	Language
Methimazole	English
ACROS	English
SigmaAldrich	English
ALFA	English

Methimazole Usage And Synthesis

Imidazole anti-thyroid drugs	Methimazole is an imidazole anti-thyroid drug, not a hormone drug, the commodity on the market is known as methylthio thiazole, it is primarily used for the treatment of hyperthyroidism, by inhibiting the peroxidase system, hindering thyroxine (T4) and tri-triiodothyronine (T3) synthesis, animal experiments show that it can inhibit B lymphocytes synthesizing antibodies, and reduce levels of thyroid stimulating antibodies in blood circulating it can make suppressing T cell function return to normal, it is applicable to hyperthyroidism caused by a variety of factors . Like other various drugs (propylthiouracil), it also has some adverse reactions while it is taken, Including hematologic adverse reactions, primarily neutropenia, hematopoietic dysfunction or disorder, thrombocytopenia, reduction of prothrombin or factor VII ; long-term medication can also cause liver damage,such as cholestatic jaundice and toxic hepatitis ; other skin reactions such as hair loss, itching, rash, dermatitis, lupus erythematosus, as well as some other rare adverse reactions. Also methimazole allows prothrombin time to prolong , and increases serum alkaline phosphatase, aspartate aminotransferase (AST) and alanine aminotransferase (ALT)and causes blood bilirubin and blood lactate dehydrogenase increasing. Therefore, patients in the medication should regularly take blood tests, liver function tests and peripheral blood leukocytes. The above information is edited by the Chemicalbook of Tian Ye.
Chemical properties	leaf-shaped crystalline (ethanol), melting point 146-148 ℃, boiling point 280 ℃ (decomposition), soluble in water, soluble in alcohol, chloroform, slightly soluble in ether, benzene.
Application	Carbimazole intermediates. anti-thyroid drugs.
Production methods	React amino acetal with methyl isothiocyanate to genarate this product. The product can also be produced from thiocyanate and N- substituted amino acetal.
Chemical Properties	White Solid
Usage	Methimazole is a thiourea antithyroid agent that prevents iodine organification, thus inhibiting the synthesis of thyroxine. Antihyperthyroid