Sulindac 38194-50-2 C20H17FO3S
Properties
Sulindac is a kind of yellow crystalline powder , with melting point 182-185 ℃, It is a non-steroidal anti-inflammatory drug. Sulindac reduces the level and activity of several cyclin-dependent kinases (CDKs) and induces apoptosis. Sulindac metabolizes to sulindac sulfide (sc-200118), a Cox (cyclooxygenase) inhibitor that represses ras signaling, and sulindac sulfone (sc-200120), an antitumor agent. Sulindac is an inhibitor of Cox-1 and Cox-2. It can be used as anti-inflammatory analgesic
Specification
Index name Spec
Appearance Yellow crystalline powder
Melting point, ℃ 182-185
Loss on Drying,% ≤0.5
Residue on Ignition, % ≤0.1
Heavy Metals ≤10ppm
Chromatographic Purity,% ≤1.0
Organic Volatile Impurity Chloroform≤500ppm
Application
1)Used for rheumatoid arthritis, arm and knee arthritis, ankylosing spondylitis, slippery bursa phlogistic, and acute gout, etc.
2)Used as anti-inflammatory analgesic
Product name Sulindac
CAS No. 38194-50-2
EINECS 253-819-2
M.F. C20H17FO3S
M.W. 356.41
Specification
Index name Spec
Appearance Yellow crystalline powder
Melting point, ℃ 182-185
Loss on Drying,% ≤0.5
Residue on Ignition, % ≤0.1
Heavy Metals ≤10ppm
Chromatographic Purity,% ≤1.0
Organic Volatile Impurity Chloroform≤500ppm
Application
1)Used for rheumatoid arthritis, arm and knee arthritis, ankylosing spondylitis, slippery bursa phlogistic, and acute gout, etc.
2)Used as anti-inflammatory analgesic
Packing
25kgs/drum
UN NO.
3249/6.1(b)
Storage
Store in a cool, dry place, away from direct heat and light.
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