Finasteride Propecia 98319-26-7
Quick Detail:Finasteride is an orally active testosterone Type II 5-alpha reductase inhibitor, inhibiting the enzyme that converts testosterone to dihydrotestosterone (DHT).
Description:
Finasteride
Alias: Proscar
CAS No: 98319-26-7
MF: C23H36N2O2
MW: 372.55
Purity: 98.5%
Appearance: white powder.
Applications:
Propecia (finasteride) is used to treat male pattern baldness (androgenic alopecia) in men. Topically (on the scalp itself) it is of some effect in minimizing further hair loss. In combination with Nizoral and spironolactone (which smells awful, by the way) it can actually reverse loss moderately.
Used for the treatment of prostate disease first. Clinical studies suggest that, with finasteride 1 mg/day, continuous oral 3 months or slightly long can have hair growth, after continuous treatment 1 year hair growth rate to 48%, and can continue to fall off, taking the hair organization 2 years hair growth rate reached 66% ~ 83%.
Specifications:
Test Items
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Specification
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Test Results
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Description
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White or off-white crystalline powder
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Off-white crystalline powder
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Specific rotation
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-56°~-60°
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-58.2°
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Identification
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IR
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Matches with working standard
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Complies
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HPLC
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Solubility
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Freely soluble in chloroform and in alcohol; Very slightly soluble in water
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Conform
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Heavy metals
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≤10ppm
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<10ppm
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Water
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≤0.3%
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0.22%
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Residue on ignition
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≤0.1%
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0.05%
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Relative material
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Maximum impurities≤0.5%
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0.36%
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Total impurities≤1.0%
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0.52%
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Assay
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98.5~101.0%
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99.68%
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Conclusion
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The specification conform with USP29
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