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CAS:134523-03-8 C66H68CaF2N4O10 Atorvastatin calcium CAS:134523-03-8 C66H68CaF2N4O10 technical grade or OLED grade CAS:134523-03-8 C66H68CaF2N4O10 factory price high purity 99%
Atorvastatin calcium Basic information |
Product Name: | Atorvastatin calcium |
Synonyms: | LIPITOR;ATORVASTATIN CALCIUM SALT;ATORVASTATIN CALCIUM;ATORVASTATIN CA;[r-(r*, r*)]-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylaminocarbonyl)-1h-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid calcium salt;1h-pyrrole-1-heptanoicacid,beta,delta-dihydroxy-2-(4-fluorophenyl)-5-(1-methy;calciumsalt(2:1),(r-(r*,r*))-lethyl)-3-phenyl-4-((phenylamino)carbonyl);ci-981 |
CAS: | 134523-03-8 |
MF: | C66H68CaF2N4O10 |
MW: | 1155.36 |
EINECS: | 200-659-6 |
Product Categories: | Active Pharmaceutical Ingredients;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Atorvastatin;Aromatics;Chiral Reagents;Pfizer compounds;Pharmaceutical intermediates;Isotope;LIPITOR;Cardiovascular APIs;Antilipemic agent;API |
Mol File: | 134523-03-8.mol |
Atorvastatin calcium Chemical Properties |
mp | 176-178°C |
storage temp. | Store at +4°C |
CAS DataBase Reference | 134523-03-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xn,T,F |
Risk Statements | 20/21/22-36/37/38-39/23/24/25-23/24/25-11 |
Safety Statements | 26-36-45-36/37-16-7 |
Atorvastatin calcium Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia |
Usage | A selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. |
Usage | antihyperlipidemic, HMGCoA reductase inhibitor |
Usage | DMSO and EtOH soluble |
Usage | The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease. |
Biological Activity | Potent HMG-CoA reductase inhibitor (IC 50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation in vitro and exhibits antinociceptive effects in the inflammatory hypernociception model. |
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