125317-39-7 125317-39-7 125317-39-7
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Vinorelbine tartrate Basic information |
Product Name: | Vinorelbine tartrate |
Synonyms: | NVB;NAVELBINE;NAVELBINE TARTRATE;VINORELBINE BITARTRATE;VINORELBINE DITARTARIC ACID;VINORELBINE DITARTRATE;VINORELBINE DITARTRATE SALT;VINORELBINE TARTRATE |
CAS: | 125317-39-7 |
MF: | C53H66N4O20 |
MW: | 1079.11 |
EINECS: | |
Product Categories: | APIs;VINORELBINE TARTRATE;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Antineoplastic;Anti-cancer & immunity;Inhibitors |
Mol File: | 125317-39-7.mol |
Vinorelbine tartrate Chemical Properties |
mp | 181-183°C |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL |
form | powder |
color | off-white |
CAS DataBase Reference | 125317-39-7(CAS DataBase Reference) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Vinorelbine tartrate Usage And Synthesis |
Chemical Properties | Pale Yellow Powder |
Usage | An antineoplastic |
Biological Activity | Selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. Inhibits proliferation of multiple human tumor cell lines (IC 50 = 1.25 nM in HeLa cells) and blocks metaphase/anaphase transition by suppression of microtubule dynamics (IC 50 = 3.8 nM). Reduces spindle length by 29% and inhibits microtubule polymerization at micromolar concentrations. |
Vinorelbine tartrate Basic information |
Product Name: | Vinorelbine tartrate |
Synonyms: | NVB;NAVELBINE;NAVELBINE TARTRATE;VINORELBINE BITARTRATE;VINORELBINE DITARTARIC ACID;VINORELBINE DITARTRATE;VINORELBINE DITARTRATE SALT;VINORELBINE TARTRATE |
CAS: | 125317-39-7 |
MF: | C53H66N4O20 |
MW: | 1079.11 |
EINECS: | |
Product Categories: | APIs;VINORELBINE TARTRATE;Intermediates & Fine Chemicals;Pharmaceuticals;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Antineoplastic;Anti-cancer & immunity;Inhibitors |
Mol File: | 125317-39-7.mol |
Vinorelbine tartrate Chemical Properties |
mp | 181-183°C |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL |
form | powder |
color | off-white |
CAS DataBase Reference | 125317-39-7(CAS DataBase Reference) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Vinorelbine tartrate Usage And Synthesis |
Chemical Properties | Pale Yellow Powder |
Usage | An antineoplastic |
Biological Activity | Selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. Inhibits proliferation of multiple human tumor cell lines (IC 50 = 1.25 nM in HeLa cells) and blocks metaphase/anaphase transition by suppression of microtubule dynamics (IC 50 = 3.8 nM). Reduces spindle length by 29% and inhibits microtubule polymerization at micromolar concentrations. |
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