72956-09-3 72956-09-3 72956-09-3
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Carvedilol Basic information |
Product Name: | Carvedilol |
Synonyms: | 1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-2-propano;CARVEDILOL;COREG;DIMITONE;DQ-2466;DILATREND;BM-14190;1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2-METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL |
CAS: | 72956-09-3 |
MF: | C24H26N2O4 |
MW: | 406.47 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Aromatics;Heterocycles;API;LEVAQUIN;Cardiovascular Drugs |
Mol File: | 72956-09-3.mol |
Carvedilol Chemical Properties |
mp | 113-117°C |
storage temp. | Store at +4°C |
Merck | 1873 |
CAS DataBase Reference | 72956-09-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | N,Xn |
Risk Statements | 51/53-36/37/38-20/21/22 |
Safety Statements | 61-36-26 |
RIDADR | UN 3077 9/PG 3 |
RTECS | UA8670000 |
HazardClass | IRRITANT |
Hazardous Substances Data | 72956-09-3(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Carvedilol | English |
Carvedilol Usage And Synthesis |
Chemical Properties | Colourless Crystalline Solid |
Usage | A nonselective -adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure. |
Usage | antibacterial |
Usage | Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure. |
Usage | veterinary use |
Usage | For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin. |
Biological Activity | Potent β -adrenoceptor and α 1 -adrenoceptor antagonist (K i values are 0.81, 0.96 and 2.2 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K + (K IR ) channels, voltage-dependent Ca 2+ channels and exhibits antioxidant properties at higher concentrations. |
Carvedilol Basic information |
Product Name: | Carvedilol |
Synonyms: | 1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-2-propano;CARVEDILOL;COREG;DIMITONE;DQ-2466;DILATREND;BM-14190;1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2-METHOXYPHENOXY)ETHYL]AMINO]-2-PROPANOL |
CAS: | 72956-09-3 |
MF: | C24H26N2O4 |
MW: | 406.47 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Adrenoceptor;Aromatics;Heterocycles;API;LEVAQUIN;Cardiovascular Drugs |
Mol File: | 72956-09-3.mol |
Carvedilol Chemical Properties |
mp | 113-117°C |
storage temp. | Store at +4°C |
Merck | 1873 |
CAS DataBase Reference | 72956-09-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | N,Xn |
Risk Statements | 51/53-36/37/38-20/21/22 |
Safety Statements | 61-36-26 |
RIDADR | UN 3077 9/PG 3 |
RTECS | UA8670000 |
HazardClass | IRRITANT |
Hazardous Substances Data | 72956-09-3(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Carvedilol | English |
Carvedilol Usage And Synthesis |
Chemical Properties | Colourless Crystalline Solid |
Usage | A nonselective -adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure. |
Usage | antibacterial |
Usage | Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure. |
Usage | veterinary use |
Usage | For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin. |
Biological Activity | Potent β -adrenoceptor and α 1 -adrenoceptor antagonist (K i values are 0.81, 0.96 and 2.2 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K + (K IR ) channels, voltage-dependent Ca 2+ channels and exhibits antioxidant properties at higher concentrations. |
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