33419-42-0 33419-42-0 33419-42-0
1. Certificate Of Analysis (COA)
2. Material Safety Data Sheet (MSDS)
3. Route of synthesis (ROS)
4. Method of Aanlysis (MOA)
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Etoposide Basic information |
Product Name: | Etoposide |
Synonyms: | VP-16;VP-16-213;4’-demethyl-epipodophyllotoxin-beta-d-ethyliden-glucosid;4’-demethylepipodophyllotoxinethylidene-beta-d-glucoside;4’-o-demethyl-1-o-(4,6-o-ethylidene-beta-d-glucopyranosyl)epipodophyllotoxin;9-((4,6-o-ethylidine-beta-d-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydro;demethyl-epipodophyllotoxinethylideneglucoside;e[qr] |
CAS: | 33419-42-0 |
MF: | C29H32O13 |
MW: | 588.56 |
EINECS: | 251-509-1 |
Product Categories: | Pharmaceutical;Heterocycles;Antitumors for Research and Experimental Use;Biochemistry;Glucose;Sugars;Apoptosis;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Antitumour;Signalling;Apoptosis Inducers;Antibiotics;Carbohydrates & Derivatives;Chiral Reagents;PARADIONE;Antineoplastic;Anti-cancer&immunity;Inhibitors |
Mol File: | 33419-42-0.mol |
Etoposide Chemical Properties |
mp | 236-251 °C(lit.) |
refractive index | -110.5 ° (C=0.6, CHCl3) |
storage temp. | Store at RT |
solubility | DMSO: 30 mg/mL |
form | powder |
color | white |
Merck | 3886 |
EPA Substance Registry System | Furo[3',4': 6,7]naphtho[2,3-d]-1,3-dioxol- 6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-. beta.-D-glucopyranosyl]oxy]- 5,8,8a,9-tetrahydro-5-(4- hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-(33419-42-0) |
Safety Information |
Hazard Codes | T,Xi |
Risk Statements | 45-22-36/37/38 |
Safety Statements | 53-45-36/37-26 |
RIDADR | 3249 |
WGK Germany | 3 |
RTECS | KC0190000 |
HazardClass | 6.1(a) |
PackingGroup | II |
Hazardous Substances Data | 33419-42-0(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Etoposide | English |
SigmaAldrich | English |
Etoposide Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | An antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor |
Usage | A DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic. |
Usage | anticonvulsant |
Biological Activity | Topoisomerase II inhibitor (IC 50 = 59.2 μ M). |
Etoposide Basic information |
Product Name: | Etoposide |
Synonyms: | VP-16;VP-16-213;4’-demethyl-epipodophyllotoxin-beta-d-ethyliden-glucosid;4’-demethylepipodophyllotoxinethylidene-beta-d-glucoside;4’-o-demethyl-1-o-(4,6-o-ethylidene-beta-d-glucopyranosyl)epipodophyllotoxin;9-((4,6-o-ethylidine-beta-d-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydro;demethyl-epipodophyllotoxinethylideneglucoside;e[qr] |
CAS: | 33419-42-0 |
MF: | C29H32O13 |
MW: | 588.56 |
EINECS: | 251-509-1 |
Product Categories: | Pharmaceutical;Heterocycles;Antitumors for Research and Experimental Use;Biochemistry;Glucose;Sugars;Apoptosis;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Antitumour;Signalling;Apoptosis Inducers;Antibiotics;Carbohydrates & Derivatives;Chiral Reagents;PARADIONE;Antineoplastic;Anti-cancer&immunity;Inhibitors |
Mol File: | 33419-42-0.mol |
Etoposide Chemical Properties |
mp | 236-251 °C(lit.) |
refractive index | -110.5 ° (C=0.6, CHCl3) |
storage temp. | Store at RT |
solubility | DMSO: 30 mg/mL |
form | powder |
color | white |
Merck | 3886 |
EPA Substance Registry System | Furo[3',4': 6,7]naphtho[2,3-d]-1,3-dioxol- 6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-. beta.-D-glucopyranosyl]oxy]- 5,8,8a,9-tetrahydro-5-(4- hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-(33419-42-0) |
Safety Information |
Hazard Codes | T,Xi |
Risk Statements | 45-22-36/37/38 |
Safety Statements | 53-45-36/37-26 |
RIDADR | 3249 |
WGK Germany | 3 |
RTECS | KC0190000 |
HazardClass | 6.1(a) |
PackingGroup | II |
Hazardous Substances Data | 33419-42-0(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
Etoposide | English |
SigmaAldrich | English |
Etoposide Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | An antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor |
Usage | A DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic. |
Usage | anticonvulsant |
Biological Activity | Topoisomerase II inhibitor (IC 50 = 59.2 μ M). |
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