Salinomycin 55721-31-8 SALINOMYCIN SODIUM SALT 2.5-HYDRATE
Salinomycin Basic information |
Chemical Properties Application production method |
Product Name: | Salinomycin |
Synonyms: | SALINOMYCIN SODIUM SALT 2.5-HYDRATE;SALINOMYCIN SV SODIUM SALT 2,5-HYDRATE;Salinomycin sodium premix;Salinomycin, monosodium salt;salinomycin monosodium salt hydrate;Salinomycin-Natrium;(2R)-2-[(5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5R,7S,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid;Salinomycin |
CAS: | 55721-31-8 |
MF: | C42H71NaO12 |
MW: | 791 |
EINECS: | 258-290-1 |
Product Categories: | Organics;Antibiotics;BactericidalAntibiotics;Chemical Structure;OthersAlphabetic;Principle;S;SA - SM;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 55721-31-8.mol |
Salinomycin Chemical Properties |
storage temp. | APPROX 4°C |
Merck | 13,8415 |
Safety Information |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | 2811 |
HazardClass | 6.1 |
PackingGroup | III |
Salinomycin Usage And Synthesis |
Chemical Properties | White or light yellow crystalline powder, slight specific smell, melting point 140-142 ℃. Soluble in acetone, chloroform, benzene, ethyl acetate, diethyl ether and methanol, almost insoluble in water. Rats by oral LD5070-100mg / kg, mice orally LD5050mg / kg, chicken LD50150mg / kg. |
Application |
Salinomycin is safe and effective coccidiostat,which has inhibitory effect on most Gram-positive bacteria ,it also has effect on chicken coccidiosis, soft Ehrlich, Ehrlich poison, giant Ehrlich, Ehrlich and heap-shaped ball Harrington insects. It can be used for chicken feed, the amount is 50-60g / t,it should be stopped during laying period, the period is 5 days. Equine animals are hanged, it causes death after use; and it is banned using it with tiamulin, oleandomycin simultaneously. The above information is edited by the chemicalbook of Tian Ye. |
production method | It is produced by fermentation of white Streptomyces (Streptomyces albus). |
Chemical Properties | Brown Solid |
Usage | Salinomycin is an ionophore agent. |
Usage | Salinomycin sodium is prepared from salinomycin taking advantage of the acidic carboxylic acid which ionises and readily forms the salt in sodium hydroxide solutions. The sodium salt is the preferred formulation in animals to prevent coccidiosis and to promote growth. Salinomycin has a high affinity for monovalent cations, particularly potassium. Recently, salinomycin has been shown to inhibit cancer stem cells. |
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