Pemetrexed disodium

Product information

Pemetrexed disodium Basic information

Product Name:	Pemetrexed disodium
Synonyms:	n-[4-[2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid disodium salt;PEMETREXED DISODIUM;PEMETREXED DISODIUM(ALIMTA);PEMETREXED SODIUM;PEMETREXED;2-[4-[2-(4-Amino-2-oxo-3,5,7-triazabicyclo[4.3.0]nona-3,8,10-trien-9-yl)ethyl]benzoyl]aminopentanedioic acid disodium salt;PEMETREXED DISODIUM 99%;PEMETREXED DISODIUM 2.5H2O
CAS:	150399-23-8
MF:	C20H19N5Na2O6
MW:	471.37
EINECS:
Product Categories:	Molecular Targeted Antineoplastic;All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Chiral Reagents;LY-231514
Mol File:	150399-23-8.mol

Pemetrexed disodium Chemical Properties

storage temp.	-20°C Freezer
CAS DataBase Reference	150399-23-8(CAS DataBase Reference)

Safety Information

Hazard Codes	T;Xi,Xi,T
Risk Statements	36/38-60-61-68
Safety Statements	36/37/39-53

 

Pemetrexed disodium Usage And Synthesis

Chemical Properties	Crystalline Solid
Usage	Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively
Usage	Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic

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