Diosmin

Diosmin
Diosmin
Diosmin

Diosmin

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,

Keywords

DIOSMETIN-7-O-RUTINOSIDE DIOSMETIN-7-RUTINOSIDE DIOSMIN

Quick Details

  • Appearance:Brown powder
  • Application:520-27-4
  • PackAge:As required
  • ProductionCapacity:100-200|Kilogram|Month
  • Storage:2-8°C
  • Transportation:By air/sea/express

Superiority:

About Certificate

 

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

 

About Service

 

1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container

 

About Company

 
HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
     Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs ,  Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East ,  Africa , South America and some other countries and areas.
    We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you  better with our high - quality products and professional team.
    We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.
     We  welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details:

Product Name: Diosmin
Synonyms: DIOSMETIN-7-O-RUTINOSIDE;DIOSMETIN-7-RUTINOSIDE;DIOSMIN;BAROSMIN;3',5,7-TRIHYDROXY-4'-METHOXYFLAVONE 7-RUTINOSIDE;3,5,7-TRIHYDROXY-4-METHOXYFLAVONE 7-RUTINOSIDE;Diosmine EP4;DIOSMINE
CAS: 520-27-4
MF: C28H32O15
MW: 608.54
EINECS: 208-289-7
Product Categories: Tetra-substituted Flavones;plant extract;ACTIVE PHARMACEUTICAL INGREDIENTS;Aromatics;Intermediates & Fine Chemicals;Oligosaccharides;Pharmaceuticals;Plant extracts;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;DIOSMIL;Inhibitors
Mol File: 520-27-4.mol
Diosmin Structure
 
Diosmin Chemical Properties
mp  277-278°C
storage temp.  2-8°C
Merck  13,3327
CAS DataBase Reference 520-27-4(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-36/37
WGK Germany  3
MSDS Information
Provider Language
SigmaAldrich English
 
Diosmin Usage And Synthesis
Pharmacological Effects Diosmin is also called Alvenor. It is a kind of drug for the treatment of hemorrhoid symptoms related to acute episodes, can also be used in the treatment of symptoms associated with venous lymphatic insufficiency (leg heavy, pain, morning acid swells discomfort).
The effects of diosmin are as below:
1, Has specific affinity to the venous system, enhance the tension system without affecting the artery of vein;
2, To the microcirculation system, decrease the blood viscosity, improve the velocity of reducing silt up;
3, Contract the lymphatic system, which can enhance lymphatic and lymph drainage speed, speed up the return relieve edema.
4, Commercially available diosmin uses micronization technology, increase the contact area after using medicine, absorb more and higher bioavailability. Suitable for all kinds of hemorrhoids and acute hemorrhoids, also can be used for the treatment of chronic venous insufficiency, such as varicose veins, leg ulcers, etc.
This information is edited by ChemicalBook Xiao Nan.
Side Effects 1, May appear nausea, vomiting, abdominal pain, dyspepsia, diarrhea, insomnia, dizziness, headache, drowsiness, anxiety and other adverse reactions.
2, There may be a few of minor gastrointestinal reactions and adverse reactions such as plant nerve function disorder, but generally mild and don't have to stop the drug.
3, Pregnant women and nursing mothers with hemorrhoids are safe to use this product.
Taboos People who allergy to any ingredients in this product are prohibited.
Attentions Hemorrhoid acute episodes: treatment with this drug can't replace any other special treatments needed for handling anus diseases. This treatment must be short. If symptoms cannot eliminate quickly, anorectal epidemiology check and review should be needed.
This product contains flavonoids which is the effective composition of glycosides in plants. Effective flavonoid content for each piece of diosmin is 450 mg, 50 mg of hesperidin, the total flavonoid glycosides composition (also called Daflon) is 500 mg. General flavonoids have certain biological activity, but low toxicity and rare allergic reactions, if any allergies, stop the drug.
Application Used in food, medicine, health products, etc
Action mechanism:
1.Enhance the vein tension, even not exceptional under high temperature condition. It has a stronger effect causing the constriction of vein than other drugs such as rutin, still can enhance the tension of the vein when the body was acidosis. Diosmin has specific affinity for vein without affecting the arterial system. 
2. Improve microcirculation. Diosmin can obviously reduce the white blood cells and vascular endothelial cell adhesion, migration, disintegrating the release of inflammatory substances, such as histamine, slow excitation peptide, complement, leukotriene, prostaglandins, and too many free radicals, reducing the permeability of capillaries and enhance its tension. Diosmin can lower blood viscosity, enhance the function of red blood cell velocity, thus reduce the microcirculation clogged. 
3. Promote lymphatic circumfluence. Diosmin can increase the speed of lymphatic drainage.
Pregnant Women and Nursing Mothers Drug Use Pregnancy women use: animal experiments did not show any teratogenic effects. So far, still no harmful reports to human.
Delivery: there is no detailed research data.
Nursing mothers use: although there is no information on drug secreted with breast milk, but treatment is not recommended during breastfeeding.
Chemical Properties Brown powder
Usage vascular protectant
Usage Naturally occurring flavonic glycoside; rhamnoglycoside of Diosmetin. Capillary protectant
 
Diosmin Preparation Products And Raw materials
 

 

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