(S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER RO-18-0647;(-)-TETRAHYDROLIPSTATIN ORLISTAT
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
About Service
1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container
About Company
Product Name: | Orlistat |
Synonyms: | (S)-2-FORMYLAMINO-4-METHYL-PENTANOIC ACID (S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]-DODECYL ESTER;RO-18-0647;(-)-TETRAHYDROLIPSTATIN;ORLISTAT;N-FORMYL-L-LEUCINE (1S)-1-[[(2S,3S)-3-HEXYL-4-OXO-2-OXETANYL]METHYL]DODECYL ESTER;XENICAL;(-)-Tetrahydrolipstatin(EquivalentToOrlistat);Orlipastat |
CAS: | 96829-58-2 |
MF: | C29H53NO5 |
MW: | 495.73 |
EINECS: | |
Product Categories: | Pharmaceutical Raw Materials;Miscellaneous Biochemicals;API;Antiobesity Agent;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;Amino Acids & Derivatives;Heterocycles;ACTOS;Other APIs;Lipid-lowering medicine reducing weight |
Mol File: | 96829-58-2.mol |
Orlistat Chemical Properties |
mp | <50 °C |
storage temp. | 2-8°C |
solubility | DMSO: 19 mg/mL |
form | solid |
color | white |
CAS DataBase Reference | 96829-58-2(CAS DataBase Reference) |
Safety Information |
WGK Germany | 3 |
RTECS | OH3167600 |
Hazardous Substances Data | 96829-58-2(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
(-)-Tetrahydrolipstatin | English |
SigmaAldrich | English |
Orlistat Usage And Synthesis |
Chemical Properties | Off-White Solid |
Usage | An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. |
Usage | antidiabetic |
Usage | Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor. |
Usage | Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity. |
Biological Activity | Hypolipemic pancreatic, gastric and carboxylester lipase inhibitor. Exhibits no activity at phospholipase A 2 , liver esterase, trypsin and chymotrypsin. Inhibits the thioesterase domain of fatty acid synthase, leading to cell cycle arrest at the G 1 /S boundary in vitro . Prevents the absorption of approximately one third of fat from food and exhibits progastrokinetic, antiobesity and antihypercholesterolemic activity in vivo . |
Orlistat Preparation Products And Raw materials |
CAS NO:1714-29-0
CAS NO:870774-25-7
CAS NO:5315-79-7
CAS NO:294881-47-3
CAS NO:352359-42-3
CAS NO:121-97-1
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View