50-28-2 C18H24O2 Estradiol 50-28-2 C18H24O2
Estradiol Basic information |
Product Name: | Estradiol |
Synonyms: | BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;(+)-3,17β-estradiol;(17b)-estra-1,3,5(10)-triene-3,17diol;(17β)-estra-1,3,5(10)-triene-3,17diol;.alpha.-Oestradiol;.beta.-Oestradiol;17-.beta.-Estra-1,3,5(10)-triene-3,17-diol |
CAS: | 50-28-2 |
MF: | C18H24O2 |
MW: | 272.38 |
EINECS: | 200-023-8 |
Product Categories: | Steroids;Estrogen;Hormone;Analytical Chemistry;Biochemistry;Environmental Endocrine Disruptors;Estradiol, etc. (Environmental Endocrine Disruptors);Hydroxysteroids;Intracellular receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API;VIVELLE;Hormone Drugs;Inhibitors |
Mol File: | 50-28-2.mol |
Estradiol Chemical Properties |
mp | 178-179 °C(lit.) |
refractive index | 80.4 ° (C=1, Dioxane) |
storage temp. | 2-8°C |
form | powder |
Merck | 14,3703 |
BRN | 1914275 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 50-28-2(CAS DataBase Reference) |
NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2) |
EPA Substance Registry System | Estra-1,3,5(10)- triene-3,17-diol (17.beta.)-(50-28-2) |
Safety Information |
Hazard Codes | T,Xn,F |
Risk Statements | 60-61-45-63-64-40-36-20/21/22-11 |
Safety Statements | 53-22-36/37/39-45-36/37-26-16 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | KG2975000 |
F | 8-10 |
HazardClass | 6.1 |
PackingGroup | III |
Hazardous Substances Data | 50-28-2(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
1,3,5-Estratriene-3,17beta-diol | English |
SigmaAldrich | English |
Estradiol Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | Potent mammalian estrogenic hormone produced by the ovary. |
Usage | Estradiol is the major estrogen secreted by the premenopausal ovary. |
Biological Activity | Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. |
Estradiol Preparation Products And Raw materials |
Raw materials | Nitrogen-->p-Toluenesulfonic acid-->Litium-->Potassium borohydride-->Biphenyl-->Acetylacetone-->1,3,5(10)-Estratrien-3-ol-17-one-->Diphenylmethane-->4-ETHYL-2-METHYLPYRIDINE-->ADD |
Estradiol Basic information |
Product Name: | Estradiol |
Synonyms: | BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;(+)-3,17β-estradiol;(17b)-estra-1,3,5(10)-triene-3,17diol;(17β)-estra-1,3,5(10)-triene-3,17diol;.alpha.-Oestradiol;.beta.-Oestradiol;17-.beta.-Estra-1,3,5(10)-triene-3,17-diol |
CAS: | 50-28-2 |
MF: | C18H24O2 |
MW: | 272.38 |
EINECS: | 200-023-8 |
Product Categories: | Steroids;Estrogen;Hormone;Analytical Chemistry;Biochemistry;Environmental Endocrine Disruptors;Estradiol, etc. (Environmental Endocrine Disruptors);Hydroxysteroids;Intracellular receptor;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API;VIVELLE;Hormone Drugs;Inhibitors |
Mol File: | 50-28-2.mol |
Estradiol Chemical Properties |
mp | 178-179 °C(lit.) |
refractive index | 80.4 ° (C=1, Dioxane) |
storage temp. | 2-8°C |
form | powder |
Merck | 14,3703 |
BRN | 1914275 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 50-28-2(CAS DataBase Reference) |
NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2) |
EPA Substance Registry System | Estra-1,3,5(10)- triene-3,17-diol (17.beta.)-(50-28-2) |
Safety Information |
Hazard Codes | T,Xn,F |
Risk Statements | 60-61-45-63-64-40-36-20/21/22-11 |
Safety Statements | 53-22-36/37/39-45-36/37-26-16 |
RIDADR | 2811 |
WGK Germany | 3 |
RTECS | KG2975000 |
F | 8-10 |
HazardClass | 6.1 |
PackingGroup | III |
Hazardous Substances Data | 50-28-2(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
1,3,5-Estratriene-3,17beta-diol | English |
SigmaAldrich | English |
Estradiol Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | Potent mammalian estrogenic hormone produced by the ovary. |
Usage | Estradiol is the major estrogen secreted by the premenopausal ovary. |
Biological Activity | Endogenous estrogen receptor (ER) agonist (K i values are 0.12 and 0.13 nM for ER α and ER β respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. |
Estradiol Preparation Products And Raw materials |
Raw materials | Nitrogen-->p-Toluenesulfonic acid-->Litium-->Potassium borohydride-->Biphenyl-->Acetylacetone-->1,3,5(10)-Estratrien-3-ol-17-one-->Diphenylmethane-->4-ETHYL-2-METHYLPYRIDINE-->ADD |
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