- Min.Order :100 Gram
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
CAS:65141-46-0 C8H9N3O4 Nicorandil CAS:65141-46-0 C8H9N3O4 Nicorandil CAS:65141-46-0 C8H9N3O4 Nicorandil
Quick Details
- Appearance:white poweder
- Application:CAS:65141-46-0 C8H9N3O4 Nicorandil
- PackAge:Plastic vacuum packaging bag or bucket
- ProductionCapacity:1|Metric Ton|Day
- Storage:under the cool and dry area
- Transportation:by express or by sea
Superiority:
| Nicorandil Basic information |
| Product Name: | Nicorandil |
| Synonyms: | n-[2-(nitroxy)ethyl]-3-pyridinecarboxamide;N-[2-(NITROOXY)ETHYL]-3-PYRIDINECARBOXAMIDE;NICORANDIL;PERISALOL;SIGMART;IKOREL;ADANCOR;2-nicotinamidoethylnitrate |
| CAS: | 65141-46-0 |
| MF: | C8H9N3O4 |
| MW: | 211.17 |
| EINECS: | 265-514-1 |
| Product Categories: | Pharmaceutical;Intermediates & Fine Chemicals;Pharmaceuticals;Potassium channel;Aromatics;Heterocycles;Ikorel;reagent;Cardiovascular APIs |
| Mol File: | 65141-46-0.mol |
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| Nicorandil Chemical Properties |
| mp | 92°C |
| storage temp. | Desiccate at +4°C |
| Nicorandil Usage And Synthesis |
| Chemical Properties | White solid |
| Usage | An antianginal |
| Usage | Antihypertensor |
| Biological Activity | K ATP channel opener and NO donor, clinically used as antianginal agent. Preferentially activates SUR2B- versus SUR2A-containing K ATP channels (EC 50 values are 10 and > 500 mM respectively) and causes 1.6-fold increase in cardiac eNOS expression. Displays coronary and peripheral vasodilatory properties, reduces both pre- and after-load, and increases coronary blood flow. Also displays cardioprotective effects, possibly through ischemic preconditioning. |
| Nicorandil Preparation Products And Raw materials |
| Raw materials | Nitric acid-->Ethanolamine-->2-N-BUTOXYETHYL METHACRYLATE-->Methyl nicotinate-->NICOTINOYL CHLORIDE HYDROCHLORIDE |
Details:
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Products Name: |
Nicorandil |
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Structural Formula: |
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Chemical Name: |
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Molecular Formula : |
C8H9N3O4 |
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Molecular weight: |
211．18 |
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CAS No.: |
65141-46-0 |
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Specifications: |
BP/EP/USP/CP |
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Use: |
White to whitish needle crystal powder, antianginal drugs |
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