PHENYLBUTAZONE 1,2-Diphenyl-2,3-dioxo-4-N-butylpyrazoline 1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine
1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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Product Name: | Phenylbutazone |
Synonyms: | PHENYLBUTAZONE;1,2-Diphenyl-2,3-dioxo-4-N-butylpyrazoline;1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine;1,2-Diphenyl-4-butyl-3,5-dioxopyrazolidine;1,2-Diphenyl-4-butyl-3,5-pyrazolidinedione;3,5-dioxe-4buty-1,diphenyl-pyrazolidine;3,5-dioxo01,2-diphenyl-4-m-butyl-pyrazolidine;3,5-Dioxo-1,2-diphenyl-4-N-butyl-pyrazolidin |
CAS: | 50-33-9 |
MF: | C19H20N2O2 |
MW: | 308.37 |
EINECS: | 200-029-0 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Inhibitors;API;AZOLID |
Mol File: | 50-33-9.mol |
Phenylbutazone Chemical Properties |
mp | 104-107 °C |
storage temp. | -20°C Freezer |
Water Solubility | <0.1 g/100 mL at 23.5 ºC |
Merck | 14,7277 |
BRN | 290080 |
Stability: | Stable. Incompatible with strong oxidizing agents, strong acids, strong bases. |
CAS DataBase Reference | 50-33-9(CAS DataBase Reference) |
NIST Chemistry Reference | Phenylbutazone(50-33-9) |
EPA Substance Registry System | 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-(50-33-9) |
Safety Information |
Hazard Codes | Xn,T,F |
Risk Statements | 36/37/38-20/21/22-42/43-45-36-11 |
Safety Statements | 36/37/39-26-45-22-53-36/37-16 |
RIDADR | 3249 |
RTECS | UQ8225000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 50-33-9(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione | English |
ACROS | English |
ALFA | English |
Phenylbutazone Usage And Synthesis |
Chemical Properties | Off-Whtie Solid |
Usage | A non-steroidal anti-inflammatory compound. An inhibitor of cyclooxygenase that is also a substrate for peroxidation by cyclooxygenase |
Usage | For the treatment of backache and ankylosing spondylitis |
General Description | Odorless white or off-white crystalline powder. Tasteless at first, but slightly bitter aftertaste. pH (aqueous solution) 8.2. |
Air & Water Reactions | Phenylbutazone is relatively stable at ambient temperatures. Aqueous decomposition of Phenylbutazone occurs by hydrolysis and oxidation. Insoluble in water. |
Reactivity Profile | Phenylbutazone is incompatible with strong oxidizers, strong acids and strong bases. . |
Fire Hazard | Flash point data for Phenylbutazone are not available; however, Phenylbutazone is probably combustible. |
Phenylbutazone Preparation Products And Raw materials |
Raw materials | Sodium methanolate-->1-Butanol-->Sodium sulfite-->Sodium ethoxide-->Diethyl malonate-->1,2-Diphenylhydrazine-->Diethyl butylmalonate-->Sodium butazolidine |
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