- Min.Order :1 Kilogram
- Purity: 98%
- Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other
Keywords
Tacrolimus 104987-11-3 manufacturer , better price with good quality
Quick Details
- Appearance:White Crystalline Solid
- Application:Pharmaceuticals
- PackAge:Depended
- ProductionCapacity:300|Kilogram|Month
- Storage:KEEP COLD
- Transportation:BY SEA OR AIR
Superiority:
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Preview |
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| Tacrolimus Basic information |
| Product Name: | Tacrolimus |
| Synonyms: | (2-propenyl)-,(3s-(3r*(e(1s*,3s*,4s*)),4s*,5r*,8s*,9e,12r*,14r*,15s*,16r*,18s*;,19s*,26ar*))-;16-dimethoxy-4,10,12,18-tetramethyl-8-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1;19-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4h,23h)-tetrone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dim;6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-5;fr900506;prograf;tsukubaenolide |
| CAS: | 104987-11-3 |
| MF: | C44H69NO12 |
| MW: | 804.02 |
| EINECS: | |
| Product Categories: | Active Pharmaceutical Ingredients;Immunosuppressant.;Intermediates & Fine Chemicals;Pharmaceuticals;API;Chiral Reagents;Fujimycin, Prograf;antibiotic;Inhibitors |
| Mol File: | 104987-11-3.mol |
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| Tacrolimus Chemical Properties |
| mp | 113-115°C |
| storage temp. | −20°C |
| solubility | DMSO: >3 mg/mL |
| form | solid |
| color | white |
| CAS DataBase Reference | 104987-11-3(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | T,Xi,Xn,F |
| Risk Statements | 25-36/37/38-36-20/21/22-11 |
| Safety Statements | 45-36-26-36/37-16 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | KD4201200 |
| Tacrolimus Usage And Synthesis |
| Chemical Properties | White Crystalline Solid |
| Usage | An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. |
| Usage | FK-506 (Tacrolimus) is a macrolide immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system |
| Usage | Tacrolimus (fujimycin) was discovered as a potent inhibitor of IL2 production in a targeted search for novel immunosuppressants. Tacrolimus acts by blocking T cell proliferation in vitro by inhibiting the generation of several lymphokines, notably the original target IL-2. Tacrolimus inhibits the activity of FK-506 binding protein, Ca2+-dependent phosphatase and calcineurin, and activates NF-κB through phosphorylation and degradation of IκBα. |
| Usage | treatment of Cushing's syndrome |
| Usage | For use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, |
| Tacrolimus Preparation Products And Raw materials |
| Raw materials | Ethyl acetate-->Celite -->Starch-->Yeast extract-->Active Calcium |
Details:
Henan Sunlake Enterprise Corporation is located in Henan Province, the central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The comany was established in june 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . These products have been being well exported to Europe , Southeast Asia , the Middle East , Africa , South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.
We are taking great efforts to provide our customers with demanded goods and professional services, continuously improve our core ability of competition and get the momentum for sustainable development ,Which finally makes us being a reliable and professional supplier in international market.
We welcome any inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
Our Advantages:
I). We have abundant professional production experience.
II). We have our own chemical factory.
III). Sample is free of charge.
IV). Reasonable Price, Excellent Quality & Attentive Service
V). Prompt reply: we can reply your inquiry and email within 24 hours.
VI). Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.
VII). We have passed the LFGB, SGS, STC, HSL and some other tests.
VIII). We have a unity cooperation team.
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