1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[4-(1,4-BENZODIOXAN-2-YL)CARPIPERAZIN-1-YL)]-6,7-DIMETHOXYQUINAZOLINE MESYLATE 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate ALFADIL
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3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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Product Name: | Doxazosin mesylate |
Synonyms: | 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[4-(1,4-BENZODIOXAN-2-YL)CARPIPERAZIN-1-YL)]-6,7-DIMETHOXYQUINAZOLINE MESYLATE;1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl) piperazine methanesulfonate;ALFADIL;CARDURA;CARDENALIN;DOXAZOSIN MESYLATE;DOXAZOSIN METHANESULFONATE;UK-33274-27 |
CAS: | 77883-43-3 |
MF: | C24H29N5O8S |
MW: | 547.58 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Antihypertensive;Intermediates & Fine Chemicals;Pharmaceuticals;Adrenoceptor;CARDURA;Cardiovascular APIs;Inhibitors |
Mol File: | 77883-43-3.mol |
Doxazosin mesylate Chemical Properties |
mp | 275-277°C |
storage temp. | Desiccate at RT |
form | powder |
color | white |
Stability: | Protect from light |
CAS DataBase Reference | 77883-43-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36/37 |
WGK Germany | 2 |
RTECS | TK8044000 |
Hazardous Substances Data | 77883-43-3(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Doxazosin mesylate Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | A selective a-1-adrenergicblocker related to prazosin |
Usage | A selective α-1-adrenergicblocker related to prazosin. |
Usage | antihypertensive |
Usage | Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate. |
Usage | Doxazosin ER is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia |
Biological Activity | Selective α 1 -adrenoceptor antagonist (pK i values are 9.0, 8.5 and 8.4 for human α 1B , α 1A and α 1D receptors respectively). Displays antihypertensive activity. |
Doxazosin mesylate Preparation Products And Raw materials |
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