Trimethoprim TMP 738-70-5
Company Name:Hefei TNJ Chemical Industry Co.,Ltd.
Registered Address:B911 Xincheng Business Center,South of Dongliu Road, Zhengwu District, Hefei, Anhui,China
Register Capital:¥12,000,000.00
Re-Register Date:2009.09.03
Register Number:340108000070345 (1-1)
Legal Person:Huwang Xiuran
Register Bureau:Hefei Administration for Industry and Commerce
Business Type:Manufacturing & Trading
Business Terms:Private owned
Legal Check Date:2014.04.03
Business Scope:Sales & Production of chemical materials; Exporting and trading of various chemicals apart from forbidden materials by Government ; Import and Export of chemical technology.
Trimethoprim, a kind of white or yellowish white powder, is melting at 199-203 °C. It is a lipotropy weak alkaline ethylamine pyrimidine bacteriostatic agent, called as sulfa-synergist, too. Typically, it is ordorless, tastes bitter, sparingly soluble in chloroform, slightly soluble in alcohol or acetate, and easily soluble in glacial acetic acid. But it is almost insoluble in water. Solubility in water is less than 0.1 g per 100 ml at 24 ºC.
CAS NO |
738-70-5 |
Cate |
Pharmaceutical Material |
Product Name |
5-((3,4,5-trimethoxyphenyl)methyl)-2,4-pyrimidinediamine |
||
molecular formula |
C14H18N4O3 |
Molecular Weigh |
290.32 |
Structural Formula |
|
||
Standard |
BP98/EP97/BP2000/CP2000 |
Package |
25Kg/(Drum) |
Specification |
Appearance:White or yellowish white powder |
||
Usage |
Cure pneogaster infection, chronic senile bronchitis, bacillary dysentery, urinary tract infection, pyelon-dphristis, enteritis typhoid, gonorrhea and some specific lesion etc |
Specification
Appearance |
White or yellowish-white powder |
Solubility |
Very slightly soluble in water, slightly soluble in alcohol |
Melting point |
199-203℃ |
Specific absorbance |
Max 287nm: 240-250 |
IR-spectrum |
Complies with the reference spectrum |
Chemical reaction |
Green fluorescence at 365nm |
Appearance of solution |
Not more intensely colored than Reference Solution BY7 |
Related substance Method A by HPLC: |
|
Impurity F |
≤0.1% |
Any single impurity |
≤0.1% |
Total impurities |
≤0.2% |
Any single impurity |
≤0.1% |
Total impurities |
≤0.2% |
Heavy metals |
≤20ppm |
Residual methanol |
≤3000ppm |
Residual DMSO |
≤5000ppm |
Impurity K(Aniline)by GC |
≤5ppm |
Loss on drying |
≤1.0% |
Sulphated ash |
≤0.1% |
Assay |
98.5%~101.0% |
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