- Min.Order :1 Kilogram
- Purity: 98%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
Naproxen 22204-53-1 manufacturer , better price with good quality
Quick Details
- Appearance:White to light yellow crystal powder
- Application: Pharmaceuticals
- PackAge:Depended
- ProductionCapacity:300|Kilogram|Month
- Storage:KEEP COLD
- Transportation:BY SEA OR AIR
Superiority:
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Preview |
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| Naproxen Basic information |
| Product Name: | Naproxen |
| Synonyms: | ()-2-(methoxy-2-naphthyl)-propionicacid;()-2-(methoxy-2-naphthyl)-propionsaeure;()-propionicaci;(+)-2-(Methoxy-2-naphthyl)-propionic acid;(+)-2-(methoxy-2-naphthyl)-propionicacid;(+)-2-(Methoxy-2-naphthyl)-propionsaeure;(+)-2-naphthaleneaceticaci;(+)-6-Methoxy-alpha-methyl-2-napthaleneacetic acid |
| CAS: | 22204-53-1 |
| MF: | C14H14O3 |
| MW: | 230.26 |
| EINECS: | 244-838-7 |
| Product Categories: | chiral;Carboxylic Acids (Chiral);Chiral Building Blocks;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Intermediates & Fine Chemicals;Pharmaceuticals;Lipid signaling;Aromatics;ALEVE;Other APIs |
| Mol File: | 22204-53-1.mol |
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| Naproxen Chemical Properties |
| mp | 152-154 °C(lit.) |
| refractive index | 67.5 ° (C=1, CHCl3) |
| storage temp. | -20°C Freezer |
| Merck | 14,6417 |
| BRN | 3591067 |
| CAS DataBase Reference | 22204-53-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Naproxen(22204-53-1) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 22-39/23/24/25-23/24/25-11 |
| Safety Statements | 36/37-45-16-7 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | UF5275000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Hazardous Substances Data | 22204-53-1(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| (+)-2-(6-Methoxy-2-naphthyl)-propionic acid | English |
| SigmaAldrich | English |
| ALFA | English |
| Naproxen Usage And Synthesis |
| Non-steroidal anti-inflammatory drugs |
Naproxen is a non-steroidal anti-inflammatory drug ,it is a PG synthase inhibitor, which can inhibit prostaglandin synthetase, it has significant analgesic and antipyretic effects, oral absorption is rapid and complete, 2 to 4 hours after a dose ,plasma concentration reaches the peak, in the blood , more than 99% is bound to plasma proteins, t1 / 2 is 13 to 14 hours, about 95% is discharged from the urine with the prototype and metabolites.it is clinically used For the treatment of rheumatic and rheumatoid arthritis , osteoarthritis, ankylosing spondylitis, gout, arthritis, tenosynovitis.it can also be used to alleviate pain caused by musculoskeletal sprains, contusions,damages and dysmenorrhea . But it should be noted that like other non-steroidal anti-inflammatory drugs, the same serious gastrointestinal adverse reactions could occur at any time while taking naproxen during treatment, so the active gastroduodenal ulcer patients are hanged, other gastrointestinal tract disease patients should take this drug under close medical supervision. The above information is edited by the Chemicalbook of Tian Ye. |
| Chemical Properties | White crystal or crystalline powder. Melting point 155.3 ℃. Soluble in acetone, soluble in methanol, ethanol, acetic acid, insoluble in benzene, practically insoluble in water. In case of light,it is color-graded, odorless, tasteless. |
| Application | It is a non-steroidal anti-inflammatory drug for the relief of fever and inflammation and pain associated with arthritis or other symptoms , it has anti-inflammatory, antipyretic and analgesic effects. Naproxen plays a role by inhibiting the cyclooxygenase, which generates prostaglandin and is one kind of enzymes related to inflammatory mediators . It is recommended to take the drug during meals to reduce stomach irritation. |
| production method | by methylation, acetylation With 2-naphthol , 6-methoxy-2-acetonaphthone is produced, then it is condensed with acid ester, then generate the product through isomerization, hydrolysis, oxidation, and split and other reactions. |
| Category | Toxic substances |
| Toxicity grading | Highly toxic |
| Acute toxicity | Oral - rat LD50 248 mg / kg; Oral - Mouse LD50: 360 mg / kg |
| Flammability and hazard characteristics | Combustible; combustion produces toxic and acrid smoke. |
| Storage Characteristics | Ventilated, low-temperature ,dry storeroom, it should be stored and transported from food raw materials separately. |
| Extinguishing agent | Water, dry powder, foam,sand |
| Chemical Properties | white to light yellow crystal powde |
| Usage | An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory |
| Naproxen Preparation Products And Raw materials |
| Raw materials | Methanol-->Toluene-->Hydrogen-->2-Naphthol-->2-Acetyl-6-methoxynaphthalene |
| Preparation Products | Naproxen sodium |
Details:
Henan Sunlake Enterprise Corporation is located in Henan Province, the central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The comany was established in june 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . These products have been being well exported to Europe , Southeast Asia , the Middle East , Africa , South America and some other countries and areas.
We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.
We are taking great efforts to provide our customers with demanded goods and professional services, continuously improve our core ability of competition and get the momentum for sustainable development ,Which finally makes us being a reliable and professional supplier in international market.
We welcome any inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!
Our Advantages:
I). We have abundant professional production experience.
II). We have our own chemical factory.
III). Sample is free of charge.
IV). Reasonable Price, Excellent Quality & Attentive Service
V). Prompt reply: we can reply your inquiry and email within 24 hours.
VI). Fast Delivery: The delivery time is about 10-20 days after receiving the deposit.
VII). We have passed the LFGB, SGS, STC, HSL and some other tests.
VIII). We have a unity cooperation team.
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