- Min.Order :100 Gram
- Purity: 99%
- Payment Terms : L/C,D/A,D/P,T/T,Other
Keywords
;fosfomycinsodiumsalt;phosphonomycinsodium HIGH purity by own lab 26016-99-9 Peptide Synthesis/Antibiotics;API;antibiotic;Antibiotics
Quick Details
- Appearance: white to brown low melting crystalline solid
- Application: 26016-99-9
- PackAge:1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25kg,50kg or as customers request
- ProductionCapacity:100|Kilogram|Month
- Storage:2-8, cold storage, to avoid light storage.
- Transportation:BY SEA /BY AIR /BY COURIER
Superiority:
| Product Name: | Disodium phosphonomycin |
| Synonyms: | (1,2-epoxypropyl)-,disodiumsalt(1r,2s)(-)-phosphonicaci;(2r-cis)-(3-methyloxiranyl)phosphonicaciddisodiumsalt;(3-methyloxiranyl)-,disodiumsalt,(2r-cis)-phosphonicaci;disodiumfosfomycin;fom-na;fosfomycindisodium;fosfomycinsodiumsalt;phosphonomycinsodium |
| CAS: | 26016-99-9 |
| MF: | C3H5Na2O4P |
| MW: | 182.02 |
| EINECS: | 247-409-2 |
| Product Categories: | chiral;Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Peptide Synthesis/Antibiotics;API;antibiotic;Antibiotics |
| Mol File: | 26016-99-9.mol |
|
|
|
| Disodium phosphonomycin Chemical Properties |
| mp | >300°C |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, colorless |
| CAS DataBase Reference | 26016-99-9(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | F,C |
| Risk Statements | 11-34 |
| Safety Statements | 16-26-36/37/39-45 |
| WGK Germany | 2 |
| RTECS | SZ7902000 |
| F | 10-21 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Disodium phosphonomycin Usage And Synthesis |
| Appearance Properties |
It appears as a white crystalline powder at room temperature, hygroscopic, easily soluble in water, heated while dissolving. Fosfomycin Sodium can combine with a bacterial cell wall synthesis enzyme, hinder bacterial cell wall synthesis related substances utilizing at the first reaction, which in turn has a bactericidal effect. have antibacterial effect for Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Neisseria gonorrhoeae, Proteus mirabilis, Salmonella typhi, Serratia bacteria, most Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus faecalis, part indole-positive Proteus and certain Klebsiella, Enterobacter bacteria. The main clinical applications of Fosfomycin Sodium include: urinary tract treatment of sensitive Gram-negative bacteria caused urinary system, infection of skin and soft tissue, respiratory, intestinal and other parts. It can also be combined with other antibiotics, the treatment of severe infections caused by susceptible strains such as sepsis, pulmonary, meningeal infections, peritonitis, adnexitis, intrauterine infections, pelvic inflammatory disease, osteomyelitis. Also in combination with vancomycin for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. |
| Pharmacological effects |
1. Broad spectrum antibiotic, high bioavailability, rapid absorption, strong anti-bacterial, not diet affected. Fosfomycin Sodium displays effects on killing Gram-positive and Gram-negative bacteria, especially Pseudomonas aeruginosa, Proteus, Salmonella, and exhibit excellent antibacterial activity for a variety of drug-resistant Staphylococcus aureus and Escherichia coli. For usage in animals, there is no drug resistance and cross-resistance. Clinical effect is good. 2. Rapid sterilization: This product is a rapid fungicide, its role is still evident after 1-2 hours. About 25% of the E. coli were killed at 1 hour after exposured to Fosfomycin Sodium (12.5μg / ml), and all died within 4-6 hours. Pseudomonas aeruginosa and Staphylococcus aureus were also all killed at 4 and 8 hours. 3. Low toxicity, little irritation on the body, no acute toxicity and adverse reactions, no increased burden on the kidney. 4. Low residue: the eliminate time for the muscles and organs to reach the residual standard is 48-72 hours. The above information is edited by the Chemicalbook of Tian Ye. |
| Indications | Mainly used for Staphylococcus aureus, streptococcus, E. coli, Salmonella and other gram-negative bacteria caused acute and chronic bowel disease treatment in chickens, ducks, pigs. |
| Usage and dosage | Used in water for livestock and poultry: every 100kg of water added the product 5-10 grams, 2 times a day, once every three days. Used in animal spices: 10-15 g of the product added to per 100kg feed, 2 times a day, once every three days. |
| Combination therapy |
For the treatment of intestinal infections, Fosfomycin Sodium can combine with β- lactam, aminoglycoside. For the treatment of respiratory and lung infections, combining with macrolides, β- lactam. For staph infections, better combined with erythromycin, rifampin. For the treatment of acute respiratory infections, sepsis, peritonitis ect., increase the dose. Need to combine with β- lactams or aminoglycosides. |
| Detection Indicator |
No. Test item Export standard CP2000 Edition 1 Traits: A white crystalline powder, odorless, taste salty white crystalline powder, odorless, salty taste 2 Discriminator: Positive reaction Positive reaction 3 Specific rotation ° -4.2 ~ -5.5 -4.2 ~ -5.5 4 Heavy Metal ≤0.0010% 0≤.0010% 5 Content ≥700μ / mg ≥700μ / mg 6 Alkalinity 9.0-10.5 9.0-10.5 7 Weight loss on drying ≤1.0% ≤1.5% (water) 8 Solution clarity ≤No. 3 / 4 turbidity standards solution ≤No. 1 turbidity standard solution 9 Color of the solution ≤Yellow No. 1 ≤ Yellow No. 1 10 Glycols ≤0.50% ≤0.50% 11 Clarity of solution: can not be detected, in compliance with (a gross point ≤8 / g, wherein a color point ≤2 / g) 12 W ≤0.002% - 13 phosphorus content - 16.2-17.9% 14 Sterile: Subject to compliance 15 Heat source/ bacterial endotoxin: compliance (heat source) compliance (bacterial endotoxin) 16 α- phenylethylamine ≤0.01% - 17 Residual amount of methanol: real 18 Residual amount of ethanol: Real The above information is the main export detection index of fosfomycin. |
| Precautions |
1. This product is mainly used for pigs, chickens, fish; application for other animals should medication under veterinary guidance. 2. Fosfomycin Sodiumand β- lactams, aminoglycosides, macrocyclic acid esters have a synergistic effect of combination therapy, and can reduce or delay the occurrence of bacterial resistance. |
| Application | For the treatment of infections caused by Staphylococcus aureus, Escherichia coli, Proteus and Shigella. |
| Chemical Properties | White Solid |
| Usage | Curariform muscle relaxants |
| Usage | Antibiotic |
Service we provide:
1. Mixed container, we can mix different items in one container.
2. Quality control, before shipment, free sample for test. after shipment, keep sample for 3 years
3. Prompt shipment with professional documents
4. Packing as your request, with photo before shipment
Details:
- Exhibition in shanghai
We have clients throughout the world：
Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.
Our Laboratoy
We have our own independent lab test center：
This makes sure that our technology support is reliable and authoritative.All of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.
Our factory
High quality with competitive price：
We are manufacturer and can provide high quality products with factory price
Package & Shipment
Fast and safe delivery：
Parcels can be sent out within 24 hours after payment. Tracking number is available
Secure and discreet shipment. You have various choices of transportation methods
You Might Also Like
Related Searches
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View