109581-93-3 C44H69NO12 TACROLIMUS

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

18-tetramethyl 3-methoxycyclohexyl tacrolimushydrate

Quick Details

Appearance:As detailed
Application:109581-93-3
PackAge:As required
ProductionCapacity:100-200|Kilogram|Month
Storage:Store at -20°C
Transportation:By air/sea/express

Superiority:

About Certificate

1.Certificate Of Analysis (COA)
2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)

About Service

1. Quality control, before shipment, free sample for test.
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment
4. Mixed containers with different mixed items in one container

About Company

HenNan sunlake enterprise corporation is located in Henan Province , The central plain of China , Which enjoys favorable geogeaphical position and convenient transportion, The com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .

Sunlake is a professional manufacturer engaged in producing and selling chemicals,including Organic & inorganic chemicals , pigments & Dyestuffs , Water treatment chemicals , Food & FEED additives and others . these products have been being well exported to europe , southeast Asia , the Middle East , Africa , South America and some other countries and areas.

We sincerely welcome foreign friends to visit our plant for cooperation. With the idea of "quality first,credit priority, Excellent service", We are highly acknowledged by customers for good quality and competitive price. More importantly , the company has a strong R & D team, who are professional engineers and scholars with Ph. D. .So we are confident to serve you better with our high - quality products and professional team.

We are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional wupplier in international market.

We welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Details:

Product Name:	TACROLIMUS
Synonyms:	FK-506;,8s,9e,12r,14r,15s,16r,18s,19s,26ar))-;18-tetramethyl-8-(2-propenyl)-,monohydrate,(3s-(3r(e(1s,3s,4s)),4s,5r;3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-9,10,12,;tacrolimushydrate;tsukubaenolidehydrate;FK-506 MONOHYDRATE;Tacarolimus
CAS:	109581-93-3
MF:	C44H69NO12
MW:	822.04
EINECS:
Product Categories:	Signalling
Mol File:	109581-93-3.mol

TACROLIMUS Chemical Properties

storage temp.

−20°C

Safety Information

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1/PG 3
RTECS	KD4201200

MSDS Information

TACROLIMUS Usage And Synthesis

Usage	immune suppressant, antifungal
Biological Activity	Potent calcineurin (protein phosphatase 2B) inhibitor that requires FK 506-binding protein 12 (FKBP12) for activity (IC 50 = 3 nM). Inhibits secretion of IL-1, IL-2 (IC 50 = 1 nM), IL-3, IL-4, IL-6 (IC 50 = 35 nM), GM-CSF, TNF α (IC 50 = 10 nM), IFN γ and Myc from activated T-cells in vitro . Exhibits potent immunosuppressive, neuroprotective and anticonvulsant activity in vivo .

TACROLIMUS Preparation Products And Raw materials

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