6-dihydroxybenzoyl 15-trimethyloxacyclooctadeca R-Tiacumicin B
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4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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Product Name: | FidaxoMicin |
Synonyms: | FidaxoMicin;3-(((6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-b-D-mannopyranosyl)oxy)-methyl)-12(R)-[(6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-b-D-lyxo-hexopyranosyl)oxy]-11(S)-ethyl-8(S)-hydroxy-18(S)-(1(R)-hydroxyethyl)-9,13,15-trimethyloxacyclooctadeca-3,5,9,13,15-pentaene-2-one;OPT-80;PAR-101;R-Tiacumicin B;FidaxoMicin(LipiarMycin);ClostoMicin B1, LipiarMycin A3, TiacuMicin B, OPT 80;Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-, (3E,5E,8S,9E,11S,12R,13E,15E,18S)- |
CAS: | 873857-62-6 |
MF: | 52H74Cl2O18 |
MW: | 0 |
EINECS: | |
Product Categories: | Inhibitors |
Mol File: | Mol File |
FidaxoMicin Chemical Properties |
density | 1.33 |
Safety Information |
FidaxoMicin Usage And Synthesis |
Usage | Fidaxomicin is a recently marketed antibiotic with a confusing history dating back to its original isolation in 1975. Fidaxomicin is the major analogue of a family of macrocyclic lactones, isolated independently by three different groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora) known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the gastrointestinal tract without undue disruption to gut microbial flora. |
FidaxoMicin Preparation Products And Raw materials |
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