Amlodipine besilate

Amlodipine besilate

Amlodipine besilate

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1 Gram

FOB Price: USD 100.0000

  • Min.Order :1 Gram
  • Purity: 99
  • Payment Terms : T/T,,MoneyGram

Keywords

Amlodipine besilate Amlodipine besilate ,C26H31ClN2O8S C26H31ClN2O8S,chemical

Quick Details

  • Appearance:powder
  • Application:Pharmaceutical Intermediates
  • PackAge:bag
  • ProductionCapacity:100|Metric Ton|Month
  • Storage:dry
  • Transportation: by air

Superiority:

Amlodipine besilate Basic information
Product Name: Amlodipine besilate
Synonyms: 2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE;2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate;AMLODIPINE BENZENESULFONATE;AMLODIPINE BESILATE;AMLODIPINE BESYLATE;NORVASC;3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,;4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
CAS: 111470-99-6
MF: C26H31ClN2O8S
MW: 567.05
EINECS:  
Product Categories: Active Pharmaceutical Ingredients;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Amlodipine;Aromatics;Dihydropyridine;Heterocycles;BENICAR;AZD929;Fine Chemical

 

Details:

 
Amlodipine besilate Usage And Synthesis
Chemical Properties White Crystalline Solid
Usage A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
Usage Angiotensin II inhibitor prodrug, antihypertensive
Usage Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Biological Activity

L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).

 
Amlodipine besilate Chemical Properties
mp  199-201°C
storage temp.  Store at RT
solubility  DMSO: 20 mg/mL
form  solid
color  white
CAS DataBase Reference 111470-99-6(CAS DataBase Reference)

 

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