5-estratriene-3 17-alpha-dihydroxyoestra-1 Oestradiol
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2.Material Safety Data Sheet (MSDS)
3.Route of synthesis (ROS)
4.Method of Aanlysis(MOA)
5.Nuclear Magnetic Resonance(NMR)
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About Company
Product Name: | Estradiol |
Synonyms: | 1,3,5-estratriene-3,17-alpha-diol;1,3,5-Estratriene-3,17alpha-diol;17alpha-Oestradiol;3,17alpha-Dihydroxyestra-1,3,5(10)-triene;3,17-alpha-dihydroxyoestra-1,3,5(10)-triene;3,17alpha-Dihydroxyoestra-1,3,5(10)-triene;5(10)-triene-3,17-diol,(17-alpha)-estra-3;epiestradial |
CAS: | 57-91-0 |
MF: | C18H24O2 |
MW: | 272.38 |
EINECS: | 200-023-8 |
Product Categories: | Steroids;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 57-91-0.mol |
Estradiol Chemical Properties |
mp | 176-180 °C(lit.) |
storage temp. | 0-6°C |
solubility | ethanol: 50 mg/mL, clear, colorless |
form | powder |
color | white with slight yellow cast |
Merck | 13,3738 |
CAS DataBase Reference | 57-91-0(CAS DataBase Reference) |
NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17alpha-diol(57-91-0) |
Safety Information |
Hazard Codes | T,Xn |
Risk Statements | 45-48-40 |
Safety Statements | 53-45-24/25-22 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | KG3750000 |
F | 8-10 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ALFA | English |
Estradiol Usage And Synthesis |
Chemical Properties | White Solid |
Usage | Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke. |
Biological Activity | Endogenous estrogen receptor ligand (K i values are 0.2 and 1.2 nM for ER α and ER β receptors respectively). |
Estradiol Preparation Products And Raw materials |
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