Bosutinib 380843-75-4,chemical C26H29Cl2N5O3,research
Product Name: | Bosutinib |
Synonyms: | SKI-606;BOSUTINIB;Bosutinib for research;4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;Bosutinib ( SKI-606 );3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-Methoxyphenyl)aMino]-6-Methoxy-7-[3-(4-Methyl-1-piperazinyl)propoxy]-;Bosutinib(TINIBS );4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile Bosutinib (SKI-606) |
CAS: | 380843-75-4 |
MF: | C26H29Cl2N5O3 |
MW: | 530.45 |
EINECS: | |
Product Categories: | API;Aromatics Compounds;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pfizer compounds;Pharmaceuticals |
Bosutinib Chemical Properties |
mp | 116-120 ºC |
density | 1.36 |
storage temp. | room temp |
CAS DataBase Reference | 380843-75-4(CAS DataBase Reference) |
Bosutinib Usage And Synthesis |
Chemical Properties | Pale Yellow Solid |
Usage | A novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. |
Usage | peripheral vasolidator increases cerebral blood flow, potential therapeutic for Altzheimer’s disease, cognitive impairment and dementia |
Usage | Bosutinib (SKI-606) is a novel, dual Src/Abl inhibitor with IC50 of 1.2 nM and 1 nM, |
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