Artemisinin 63968-64-9 ARTEMISININ;ARTEANNUIN
Artemisinin Basic information |
Product Name: | Artemisinin |
Synonyms: | [3r-(3r,5as,6s,8as,9r,10r,12s,12ar**)]-decahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin-10-one;ALPHA BETA ARTEMISININ;ARTEMISINE;ARTEMISIA P E;ARTEMISIA ANNUA;ARTEMISININE;ARTEMISININ;ARTEANNUIN |
CAS: | 63968-64-9 |
MF: | C15H22O5 |
MW: | 282.33 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Miscellaneous Natural Products;Others (Antibiotics for Research and Experimental Use);Antibiotics for Research and Experimental Use;Biochemistry;Standard extract;Natural Plant Extract;Intermediates & Fine Chemicals;Pharmaceuticals;Miscellaneous Compounds;Chiral Reagents;Heterocycles;Plant extract;sy;Herb extract;API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Antimalarial;Inhibitors |
Mol File: | 63968-64-9.mol |
Artemisinin Chemical Properties |
mp | 156-157 °C(lit.) |
alpha | 76 º (c=0.5,MeOH) |
refractive index | 75 ° (C=0.5, MeOH) |
storage temp. | Store at +4°C |
Merck | 817 |
Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. May absorb, and react with, carbon dioxide from the air. |
Safety Information |
Safety Statements | 22-24/25 |
WGK Germany | 2 |
RTECS | KD4170000 |
HS Code | 29322985 |
MSDS Information |
Provider | Language |
---|---|
(+)-Arteannuin | English |
SigmaAldrich | English |
Artemisinin Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | Active antimalarial constituent of the tradional Chinese medicinal herb Artemisia annua L., Compositae, which has been known for almost 2000 years as Qinghao. Antimalarial |
Biological Activity | Antimalarial agent; interacts with heme to produce carbon-centred free radicals, causes protein alkylation and damages parasite microorganelles and membranes. Also selectively inhibits the P-type ATPase (PfATP6) of Plasmodium falciparum (K i ~ 150 nM). Displays antiangiogenic effects in mouse embryonic stem cell-derived embryoid bodies. |
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