Acyclovir 59277-89-3 Acycolguanosine
Acyclovir Basic information |
Product Name: | Acyclovir |
Synonyms: | 1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on;aciclovirum(latin);aclovir;Acycolguanosine;bw248u;vipral;virorax |
CAS: | 59277-89-3 |
MF: | C8H11N5O3 |
MW: | 225.2 |
EINECS: | 261-685-1 |
Product Categories: | PHARMACEUTICALS;Active Pharmaceutical Ingredients;Purine;Nucleotides and Nucleosides;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Amines;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;API's;Valacyclovir Hydrochloride Monohydrate;Antiviral;Herpes Viruses;Anti-virals;THALOMID;inhibitor |
Mol File: | 59277-89-3.mol |
Acyclovir Chemical Properties |
mp | 256-257°C |
storage temp. | −20°C |
solubility | H2O: 0.7 mg/mL |
form | powder |
color | white |
Merck | 146 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 59277-89-3(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-40-20/21/22 |
Safety Statements | 22-24/25-36-26-23 |
WGK Germany | 2 |
RTECS | UP0791400 |
HazardClass | IRRITANT |
Hazardous Substances Data | 59277-89-3(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
2-Amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6H-purin-6-one | English |
SigmaAldrich | English |
Acyclovir Usage And Synthesis |
Chemical Properties | white to light yellow crystal powder |
Usage | Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral |
Usage | hypnotic |
Biological Activity | Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC 50 values are 0.85 and 0.86 μ M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy). |
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