Chelerythrine chloride 34316-15-9,chemical research,C21H18NO4+
Product Name: | Chelerythrine chloride |
Synonyms: | CHELERYTHRINE(TODDALINE)(RG);1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium;1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride;Chelerythrine chloride;1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;2,3-(Epoxymethanoxy)-5-methyl-7,8-dimethoxybenzo[c]phenanthridine-5-ium;Cheleritrine;3895-92-9 (Chloride) |
CAS: | 34316-15-9 |
MF: | C21H18NO4+ |
MW: | 348.37192 |
EINECS: | 251-930-0 |
Product Categories: | Natural Plant Extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
helerythrine chloride Chemical Properties |
mp | 195-205°C |
storage temp. | Desiccate at -20°C |
CAS DataBase Reference | 34316-15-9(CAS DataBase Reference) |
Chelerythrine chloride Usage And Synthesis |
Biological Activity | Potent, cell-permeable inhibitor of protein kinase C (IC 50 = 660 nM); competitive with respect to the phosphate acceptor and non-competitive with respect to ATP. Has a wide range of biological activities, including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. Activates MAPK pathways, independent of PKC inhibition. Inhibits binding of BclXL to Bak (IC 50 = 1.5 μ M) or Bad proteins and stimulates apoptosis. |
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