Sarpogrelate hydrochloride 135159-51-2,chemical research,C24H32ClNO6
Product Name: | Sarpogrelate hydrochloride |
Synonyms: | (+/-)-2-(dimethylamino)-1-{[o-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride;SARPOGRELATE HCL;SARPOGRELATE HYDROCHLORIDE;Anplag;Butanedioic acid, mono[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester, hydrochloride (9CI);Butanedioic acid, mono[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester, hydrochloride, (+-)-;MCI 9042;(+/-)-2-(Dimethylamino)-1-{[o-(m-methoxyphenethyl)phenoxy]methyl}ethyl hydrogen succinate hydrochloride |
CAS: | 135159-51-2 |
MF: | C24H32ClNO6 |
MW: | 465.96698 |
Sarpogrelate hydrochloride Chemical Properties |
mp | 145-148°C |
storage temp. | Desiccate at RT |
CAS DataBase Reference | 135159-51-2(CAS DataBase Reference) |
Sarpogrelate hydrochloride Usage And Synthesis |
Chemical Properties | White Solid |
Usage | Sarpogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist ress-induced hemolysis. |
Biological Activity | Selective 5-HT 2A receptor antagonist (pK i values are 8.52, 7.43 and 6.57 for 5-HT 2A , 5-HT 2C and 5-HT 2B receptors respectively). Displays selectivity over 5-HT 1 , 5-HT 3 , 5-HT 4 H 1 , H 2 , M 3 , α 1 -adrenergic, α 2 -adrenergic and β -adrenergic receptors. Displays cardioprotective activity in vivo . |
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