Lansoprazole 103577-45-3,chemical research,C16H14F3N3O2S
Product Name: | Lansoprazole |
Synonyms: | 1h-benzimidazole,2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)su;2-(((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1h-benz;lfinyl)-;PREVACID;OGAST;LANSOPRAZOLE;LANSAPRAZOLE;LANSOX |
CAS: | 103577-45-3 |
MF: | C16H14F3N3O2S |
MW: | 369.36 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Ion Pump Inhibitors;Monovalent Ion Channels;Voltage-gated Ion Channels;ATPase;Pharmaceutical Intermediates;API Reference StandardFree Base API;Other APIs;pharmaceutical |
Lansoprazole Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | Used as a gastric proton pump inhibitor. An antiulcerative |
Usage | anthelmintic |
Usage | A H+,K+-ATPase inhibitor that displays antisecretory activity |
Usage | Treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, duodenal ulcers, Helicobacter pylori (H. pylori) infections,stomach ulcers, prevention of stomach ulcers in those people taking non-steroidal anti-inflammatory drugs (NSAIDs), such |
Usage | For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use. |
Biological Activity | H + ,K + -ATPase inhibitor (IC 50 = 6.3 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.09 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro . Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole (5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole ). |
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