ROTENONE 83-79-4 (-)-cis-rotenone
ROTENONE Chemical Properties |
mp | 159-164 °C(lit.) |
bp | 210-220 °C0.5 mm Hg(lit.) |
alpha | -115 º (C=1.4 IN CHLOROFORM) |
storage temp. | Store at RT |
Merck | 13,8350 |
Stability: | Stable, but light and air sensitive. Combustible. Incompatible with oxidizing agents, especially in the presence of alkalies. |
NIST Chemistry Reference | Rotenone(83-79-4) |
EPA Substance Registry System | [1]Benzopyrano[3, 4-b]furo[2,3-h][1]benzopyran- 6(6aH)-one, 1,2,12,12a-tetrahydro-8,9- dimethoxy-2-(1-methylethenyl)-, (2R,6aS,12aS)-(83-79-4) |
Safety Information |
Hazard Codes | T,N |
Risk Statements | 25-36/37/38-50/53 |
Safety Statements | 22-24/25-36-45-60-61 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | DJ2800000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Hazardous Substances Data | 83-79-4(Hazardous Substances Data) |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ACROS | English |
ROTENONE Usage And Synthesis |
Chemical Properties | white or off-white powder |
Usage | acaricide, ectoparasiticide, antineoplastic, mitochondrial poison |
Usage | Rotenone is an broad spectrum insecticide that occurs naturally in seeds and stems of several plants. |
General Description | Colorless to brownish crystals or a white to brownish-white crystalline powder. Has neither odor nor taste. |
Air & Water Reactions | ROTENONE decomposes upon exposure to light or air. Insoluble in water. |
Reactivity Profile | ROTENONE is readily oxidized in the presence of alkalis. ROTENONE is incompatible with oxidizers. . |
Fire Hazard | Flash point data for ROTENONE are not available; however, ROTENONE is probably combustible. |
Biological Activity | Mitochondrial electron transport chain inhibitor (IC 50 = 1.7 - 2.2 μ M at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC 50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. Cell-permeable and brain penetrant. |
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